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Original Articles
- The Clinical Characterization of Blocking Tics in Patients With Tourette Syndrome
- José Fidel Baizabal-Carvallo, Joseph Jankovic
- J Mov Disord. 2023;16(2):163-167. Published online March 7, 2023
- DOI: https://doi.org/10.14802/jmd.22122
- 3,120 View
- 160 Download
- 1 Web of Science
- 4 Crossref
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Abstract
PDF
Supplementary Material - Objective
Tourette syndrome (TS) is a neurodevelopmental disorder characterized by the presence of motor and phonic tics. Blocking phenomena, characterized by arrests in motor activity causing interruptions in movements or speech, have also been described in patients with TS. In this study, we aimed to characterize the frequency and features of blocking tics in patients with TS.
Methods
We studied a cohort of 201 patients with TS evaluated at our movement disorders clinic.
Results
We identified 12 (6%) patients with blocking phenomena. Phonic tic intrusion causing speech arrest was the most common (n = 8, 4%), followed by sustained isometric muscle contractions arresting body movements (n = 4, 2%). The following variables were statistically related to blocking phenomena: shoulder tics, leg tics, copropraxia, dystonic tics, simple phonic tics, and number of phonic tics per patient (all p < 0.050). In the multivariate regression, the presence of dystonic tics (p = 0.014) and a higher number of phonic tics (p = 0.022) were associated with blocking phenomena.
Conclusion
Blocking phenomena are present in approximately 6% of patients with TS, and the presence of dystonic tics and a higher frequency and number of phonic tics increase the risk for these phenomena. -
Citations
Citations to this article as recorded by
- Tics emergencies and malignant tourette syndrome: Assessment and management
José Fidel Baizabal-Carvallo, Andrea E. Cavanna, Joseph Jankovic
Neuroscience & Biobehavioral Reviews.2024; 159: 105609. CrossRef - Tourette syndrome research highlights from 2023
Andreas Hartmann, Per Andrén, Cyril Atkinson-Clement, Virginie Czernecki, Cécile Delorme, Nanette Mol Debes, Simon Morand-Beaulieu, Kirsten Müller-Vahl, Peristera Paschou, Natalia Szejko, Apostolia Topaloudi, Kevin J. Black
F1000Research.2024; 13: 677. CrossRef - Tourette syndrome research highlights from 2023
Andreas Hartmann, Per Andrén, Cyril Atkinson-Clement, Virginie Czernecki, Cécile Delorme, Nanette Mol Debes, Simon Morand-Beaulieu, Kirsten Müller-Vahl, Peristera Paschou, Natalia Szejko, Apostolia Topaloudi, Kevin J. Black
F1000Research.2024; 13: 677. CrossRef - Oromandibular tics associated with Tourette syndrome
José Fidel Baizabal-Carvallo, Marlene Alonso-Juarez, Joseph Jankovic
Journal of Neurology.2023; 270(5): 2591. CrossRef
- Tics emergencies and malignant tourette syndrome: Assessment and management
- Premonitory Urges Reconsidered: Urge Location Corresponds to Tic Location in Patients With Primary Tic Disorders
- Jana Essing, Ewgeni Jakubovski, Nikolas Psathakis, Sinan N Cevirme, James F Leckman, Kirsten R Müller-Vahl
- J Mov Disord. 2022;15(1):43-52. Published online January 25, 2022
- DOI: https://doi.org/10.14802/jmd.21045
- 6,741 View
- 231 Download
- 11 Web of Science
- 15 Crossref
-
Abstract
PDFSupplementary Material
- Objective
In patients with Tourette syndrome and other primary tic disorders (PTDs), tics are typically preceded by premonitory urges (PUs). To date, only a few studies have investigated the location and frequency of PUs, and contrary to clinical experience, the results suggest that PUs are not located in the same anatomic region as the tics. This study aimed to further explore PU location and frequency in detail, differentiating the kind and complexity of the corresponding tics, in a large sample of patients with PTD.
Methods
A total of 291 adult (≥ 18 years) patients with a confirmed diagnosis of chronic PTD were included. The study was conducted online, assement included tics and the general characterization of PUs and a sophisticated body drawing for locating PUs.
Results
We found that PUs were located in the same body area as, or in direct proximity to, the corresponding tic. Most frequently, PUs were located in the face and at the head (62.1%). Compared with simple tics, complex (motor and vocal) tics were more often preceded by a PU; but there was no difference in PU frequency observed between motor tics and vocal tics. PUs were more often experienced at the front than at the back of the body (73% vs. 27%), while there was no difference between the right and left sides (41.6% vs. 41.3%).
Conclusion
The strong association between PU and tic location further supports the hypothesis that PUs represent the core of PTD. Accordingly, future therapies should focus on treating PUs to achieve greater tic reduction. -
Citations
Citations to this article as recorded by- Door-To-Door Video-Enhanced Prevalence Study of Tourette Disorder Among African Americans
Catherine Striley, Kevin J. Black, Natalie E. Chichetto, Lauren Vagelakos
Evidence-Based Practice in Child and Adolescent Mental Health.2024; 9(2): 281. CrossRef - Functional Tic‐Like Behaviors: A Common Comorbidity in Patients with Tourette Syndrome
Kirsten R. Müller‐Vahl, Anna Pisarenko, Carolin Fremer, Martina Haas, Ewgeni Jakubovski, Natalia Szejko
Movement Disorders Clinical Practice.2024; 11(3): 227. CrossRef - Parent-Report Sleep Disturbances and Everyday Executive Functioning Difficulties in Children with Tourette Syndrome
Lisa Keenan, Jessica Bramham, Michelle Downes
Developmental Neuropsychology.2024; 49(1): 39. CrossRef - Premonitory Urge in Patients with Tics and Functional Tic‐like Behaviors
Natalia Szejko, Julian Fletcher, Davide Martino, Tamara Pringsheim
Movement Disorders Clinical Practice.2024; 11(3): 276. CrossRef - A meta-analysis of transcranial magnetic stimulation in Tourette syndrome
Elizabeth R. Steuber, Joseph F. McGuire
Journal of Psychiatric Research.2024; 173: 34. CrossRef - Sensory Phenomenon Assessment Scale: a new tool for assessment of tic-associated sensations
Xianbin Wang, Yanlin Li, Liping Yu, Hui Xu, Anyi Zhang, Wenyan Zhang, Zhongliang Jiang, Yonghua Cui, Ying Li
Frontiers in Psychiatry.2024;[Epub] CrossRef - We've all been wrong about provisional tic disorder
Sarah C. Grossen, Amanda L. Arbuckle, Emily C. Bihun, Jonathan M. Koller, David Y. Song, Angela M. Reiersen, Bradley L. Schlaggar, Deanna J. Greene, Kevin J. Black
Comprehensive Psychiatry.2024; 134: 152510. CrossRef - Validation and assessment of the self-injurious behavior scale for tic disorders (SIBS-T)
Natalia Szejko, Heike große Schlarmann, Anna Pisarenko, Martina Haas, Valerie Brandt, Ewgeni Jakubovski, Kirsten R. Müller-Vahl
Scientific Reports.2024;[Epub] CrossRef - Premonitory Urge and Tic Severity, Comorbidities, and Quality of Life in Chronic Tic Disorders
Valerie Brandt, Jana Essing, Ewgeni Jakubovski, Kirsten Müller‐Vahl
Movement Disorders Clinical Practice.2023; 10(6): 922. CrossRef - Motor awareness, volition, and the cortical neurophysiology of simple motor tics
Aysegul Gunduz, Christos Ganos
Clinical Neurophysiology.2023; 151: 130. CrossRef - Tourette syndrome research highlights from 2022
Andreas Hartmann, Per Andrén, Cyril Atkinson-Clément, Virginie Czernecki, Cécile Delorme, Nanette Marinette Monique Debes, Kirsten Müller-Vahl, Peristera Paschou, Natalia Szejko, Apostolia Topaloudi, Keisuke Ueda, Kevin J. Black
F1000Research.2023; 12: 826. CrossRef - Tourette syndrome research highlights from 2022
Andreas Hartmann, Per Andrén, Cyril Atkinson-Clément, Virginie Czernecki, Cécile Delorme, Nanette Marinette Monique Debes, Kirsten Müller-Vahl, Peristera Paschou, Natalia Szejko, Apostolia Topaloudi, Keisuke Ueda, Kevin J. Black
F1000Research.2023; 12: 826. CrossRef - Clinical evaluation of premonitory urges in children and adolescents using the Chinese version of Individualized Premonitory Urge for Tics Scale
Guanghua Che, Wenjing Ren, Joseph F. McGuire, Ping Li, Zhiruo Zhao, Jing Tian, Jinyuan Zhang, Yue Zhang
Frontiers in Psychiatry.2023;[Epub] CrossRef - Mass social media-induced illness presenting with Tourette-like behavior
Carolin Fremer, Natalia Szejko, Anna Pisarenko, Martina Haas, Luise Laudenbach, Claudia Wegener, Kirsten R. Müller-Vahl
Frontiers in Psychiatry.2022;[Epub] CrossRef - Tics bei Erwachsenen
Tina Rawish, Gesine Sallandt, Alexander Münchau
NeuroTransmitter.2022; 33(12): 38. CrossRef
- Door-To-Door Video-Enhanced Prevalence Study of Tourette Disorder Among African Americans
Case Report
- Vocal Polyps in Tourette Syndrome
- Michael P Chu, Karen PM Chu, Kevin Fung
- J Mov Disord. 2011;4(2):80-81.
- DOI: https://doi.org/10.14802/jmd.11018
- 8,097 View
- 34 Download
- 1 Crossref
-
Abstract
PDF
Hoarseness and dysphonia are often a result of vocal cord polyps which in turn, are linked to vocal trauma. We report the case of vocal polyps in the setting of a 27-year old male with a history only remarkable for Tourette syndrome. We review the literature regarding etiology and pathophysiology of vocal cord lesions and propose vocal tics in Tourette syndrome as an under-recognized etiology. In this way, we also review therapies that may aid in treating not only the vocal cord lesions but also particularly in the setting of vocal tics.
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Citations
Citations to this article as recorded by- DISTRIBUTION OF BENIGN LARYNGEAL TUMORS IN CORRELATION WITH DURATION OF CIGARETTE SMOKING
Slaviša Radosavljević, Miško Živić, Marija Conić-Miletić, Biljana Kostić-Inić
Acta Medica Medianae.2017; 56(2): 13. CrossRef
- DISTRIBUTION OF BENIGN LARYNGEAL TUMORS IN CORRELATION WITH DURATION OF CIGARETTE SMOKING
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