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Case Report
Hot Cross Bun Sign Following Bilateral Pontine Infarction: A Case Report
Sook Young Roh, Hyun-soon Jang, Yoon Hee Kim
J Mov Disord. 2013;6(2):37-39.   Published online October 30, 2013
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  • 12 Crossref
AbstractAbstract PDF

The hot cross bun sign is characterized by cruciform T2 signal hyperintensity in the pons and has been reported to be a specific but not pathognomic for multiple system atrophy. It reflects degeneration of pontine neurons and transverse pontocerebellar fibers, regardless of the underlying pathogenic process. Here, we report a case of hot cross bun sign following bilateral pontine infarction due to Wallerian degeneration of the pontocerebellar fibers.


Citations to this article as recorded by  
  • A case of bilateral middle cerebellar peduncle infarction with hot cross bun sign
    Daisuke Kuzume, Yuko Morimoto, Satoshi Tsutsumi, Masahiro Yamasaki, Naohisa Hosomi
    Rinsho Shinkeigaku.2024; 64(3): 190.     CrossRef
  • Hot Cross Bun Sign in Bilateral Middle Cerebellar Peduncle Infarction
    Katsuya Nishida, Naonobu Futamura
    Stroke.2023;[Epub]     CrossRef
  • Hot Cross Bun Sign in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
    Chen Ling, Haotian Yan, Yun Yuan, Qing Peng
    Stroke.2023;[Epub]     CrossRef
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    Ruo-Nan Duan, Jing-Zhen He, Li-Li Cao
    The Cerebellum.2023; 23(3): 1204.     CrossRef
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    Mange Liu, Haitao Ren, Nan Lin, Ying Tan, Siyuan Fan, Hongzhi Guan
    Frontiers in Neurology.2022;[Epub]     CrossRef
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    Movement Disorders Clinical Practice.2022; 9(8): 1105.     CrossRef
  • Multiple system atrophy mimicry in MRI: Watch out for paraneoplastic rhombencephalitis
    Elena Schlapakow, Vera C. Keil, Marie Paus, Cornelia Kornblum, Elke Hattingen, Thomas Klockgether
    Journal of Clinical Neuroscience.2020; 76: 238.     CrossRef
  • Various Diseases and Clinical Heterogeneity Are Associated With “Hot Cross Bun”
    Shuzhen Zhu, Hualing Li, Bin Deng, Jialing Zheng, Zifeng Huang, Zihan Chang, Yanjun Huang, Zhibo Wen, Yanran Liang, Mengjue Yu, Ling-Ling Chan, Eng-King Tan, Qing Wang
    Frontiers in Aging Neuroscience.2020;[Epub]     CrossRef
  • The ‘Hot Cross Bun’ Sign Is Not Always Multiple System Atrophy: Etiologies of 11 Cases
    Christopher Way, David Pettersson, Amie Hiller
    Journal of Movement Disorders.2019; 12(1): 27.     CrossRef
  • Role of Magnetic Resonance Imaging in the Diagnosis of Multiple System Atrophy
    Han‐Joon Kim, Beomseok Jeon, Victor S.C. Fung
    Movement Disorders Clinical Practice.2017; 4(1): 12.     CrossRef
  • Paraneoplastic neurological syndrome due to burned-out testicular tumor showing hot cross-bun sign
    H. Ishikawa, N. Kawada, A. Taniguchi, K. Odachi, A. Mizutani, M. Asahi, H. Tomimoto
    Acta Neurologica Scandinavica.2016; 133(5): 398.     CrossRef
  • Diagnosis and differential diagnosis of MSA: boundary issues
    Han-Joon Kim, Beom S. Jeon, Kurt A. Jellinger
    Journal of Neurology.2015; 262(8): 1801.     CrossRef

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