Parkinson’s disease (PD) is a chronic, neurodegenerative movement disorder that typically affects elderly patients. Swallowing disorders are highly prevalent in PD and can have grave consequences, including pneumonia, malnutrition, dehydration and mortality. Neurogenic dysphagia in PD can manifest with both overt clinical symptoms or silent dysphagia. Regardless, early diagnosis and objective follow- up of dysphagia in PD is crucial for timely and appropriate care for these patients. In this review, we provide a comprehensive summary of the electrophysiological methods that can be used to objectively evaluate dysphagia in PD. We discuss the electrophysiological abnormalities that can be observed in PD, their clinical correlates and the pathophysiology underlying these findings.
Citations
Citations to this article as recorded by
Impact of autonomic symptoms on the clinical course of Parkinson’s disease Hiroaki Fujita, Keitaro Ogaki, Tomohiko Shiina, Hirotaka Sakuramoto, Narihiro Nozawa, Keisuke Suzuki Neurological Sciences.2024;[Epub] CrossRef
Electrokinesiographic Study of Oropharyngeal Swallowing in Neurogenic Dysphagia Enrico Alfonsi, Massimiliano Todisco, Mauro Fresia, Cristina Tassorelli, Giuseppe Cosentino Dysphagia.2023; 38(2): 543. CrossRef
Respiratory-Swallow Coordination in Individuals with Parkinson’s Disease: A Systematic Review and Meta-Analysis Rabab Rangwala, Raneh Saadi, Jungwha Julia Lee, Erin L. Reedy, Cagla Kantarcigil, Megan Roberts, Bonnie Martin-Harris Journal of Parkinson's Disease.2023; 13(5): 681. CrossRef
History of Oropharyngeal Organs and Swallowing Cumhur Ertekin, İbrahim Aydoğdu Turkish Journal Of Neurology.2023; 29(3): 165. CrossRef
Wearable, epidermal devices for assessment of swallowing function Tarek Rafeedi, Abdulhameed Abdal, Beril Polat, Katherine A. Hutcheson, Eileen H. Shinn, Darren J. Lipomi npj Flexible Electronics.2023;[Epub] CrossRef
Endoscopic Characteristics of Dysphagia in Multiple System Atrophy Compared to Parkinson's Disease Annemarie Vogel, Inga Claus, Sigrid Ahring, Doreen Gruber, Aiden Haghikia, Ulrike Frank, Rainer Dziewas, Georg Ebersbach, Florin Gandor, Tobias Warnecke Movement Disorders.2022; 37(3): 535. CrossRef
Deep Learning Analysis to Automatically Detect the Presence of Penetration or Aspiration in Videofluoroscopic Swallowing Study Jeoung Kun Kim, Yoo Jin Choo, Gyu Sang Choi, Hyunkwang Shin, Min Cheol Chang, Donghwi Park Journal of Korean Medical Science.2022;[Epub] CrossRef
Pilot study of a novel transmembranous electromyography device for assessment of oral cavity and oropharyngeal muscles Deepak Menon, Perry Mansfield, Derrick Cordice, Chris Studer, Michael O'Leary, Geoffrey Sheean, Vera Bril Muscle & Nerve.2022; 65(3): 303. CrossRef
Role of Catechol-O-methyltransferase Val158Met Polymorphism on Transcranial Direct Current Stimulation in Swallowing Hyemi Hwang, Yeonjae Han, Geun-Young Park, Soohwan Lee, Hae-Yeon Park, Sun Im Journal of Personalized Medicine.2022; 12(3): 488. CrossRef
Parkinson Hastalığında Yutma Bozukluklarına Yaklaşım Merve SAPMAZ ATALAR, Gençer GENÇ Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi.2022; 9(2): 189. CrossRef
A new swallowing supplement for dysphagia in patients with Parkinson’s disease Eungseok Oh, Sungju Jee, Beom Keun Kim, Jung Seon Lee, Kanghee Cho, Soyoung Ahn Neurological Sciences.2021; 42(5): 1949. CrossRef
The Potential of Electromyography Signals as Markers to Detect and Monitor Parkinson’s Disease Elta Diah Pasmanasari, Jeanne Adiwinata Pawitan Biomedical and Pharmacology Journal.2021; 14(1): 373. CrossRef
Autonomic dysfunction in Parkinson’s disease: Implications for pathophysiology, diagnosis, and treatment Zhichun Chen, Guanglu Li, Jun Liu Neurobiology of Disease.2020; 134: 104700. CrossRef
Prevalence and characterisation of vocal fold motion impairment (VFMI) in patients with Multiple system atrophy compared with Parkinson's disease S. Grimaldi, M. Renaud, D. Robert, A. Lagier, H. Somma, S. Soulayrol, D. Korchia, F. Fluchère, O. Lagha-Boukbiza, M. Schaeffer, T. Witjas, J.-P. Azulay, A. Eusebio Revue Neurologique.2020; 176(7-8): 608. CrossRef
A comprehensive review of the diagnosis and treatment of Parkinson’s disease dysphagia and aspiration Bhavana Patel, Joseph Legacy, Karen W. Hegland, Michael S. Okun, Nicole E. Herndon Expert Review of Gastroenterology & Hepatology.2020; 14(6): 411. CrossRef
Effects of age and gender on swallowing activity assessed by electromyography and laryngeal elevation Hiroshi Endo, Nobuyuki Ohmori, Manabu Chikai, Hiroyasu Miwa, Shuichi Ino Journal of Oral Rehabilitation.2020; 47(11): 1358. CrossRef
Swallow-breathing coordination during incremental ascent to altitude Alyssa Huff, Trevor A. Day, Mason English, Mitchell D. Reed, Shaelynn Zouboules, Gurkarn Saran, Jack K. Leacy, Carli Mann, Joel D.B. Peltonen, Ken D. O’Halloran, Mingma T. Sherpa, Teresa Pitts Respiratory Physiology & Neurobiology.2019; 265: 121. CrossRef
Swallowing in Parkinson’s disease: How is it affected? Ebru Umay, Erhan Ozturk, Eda Gurcay, Oguz Delibas, Feyza Celikel Clinical Neurology and Neurosurgery.2019; 177: 37. CrossRef
NEURAL CONTROL OF SWALLOWING Milton Melciades Barbosa COSTA Arquivos de Gastroenterologia.2018; 55(suppl 1): 61. CrossRef
Soft Electronics Enabled Ergonomic Human-Computer Interaction for Swallowing Training Yongkuk Lee, Benjamin Nicholls, Dong Sup Lee, Yanfei Chen, Youngjae Chun, Chee Siang Ang, Woon-Hong Yeo Scientific Reports.2017;[Epub] CrossRef
Improving surface EMG burst detection in infrahyoid muscles during swallowing using digital filters and discrete wavelet analysis Sebastian Restrepo-Agudelo, Sebastian Roldan-Vasco, Lina Ramirez-Arbelaez, Santiago Cadavid-Arboleda, Estefania Perez-Giraldo, Andres Orozco-Duque Journal of Electromyography and Kinesiology.2017; 35: 1. CrossRef
Spontaneous yawning in patients with multiple sclerosis: A polygraphic study Hülya Uluğut Erkoyun, Yeşim Beckmann, Nazlı Gamze Bülbül, Tülay Kurt İncesu, Nevin Gürgör Kanat, Cumhur Ertekin Multiple Sclerosis and Related Disorders.2017; 17: 179. CrossRef
Parkinson Disease-Mediated Gastrointestinal Disorders and Rational for Combinatorial Therapies Syed Ali, Ning Yin, Arkam Rehman, Verline Justilien Medical Sciences.2016; 4(1): 1. CrossRef
Clinical Characteristics and Lesions Responsible for Swallowing Hesitation After Acute Cerebral Infarction Tsukasa Saito, Keisuke Hayashi, Hajime Nakazawa, Tetsuo Ota Dysphagia.2016; 31(4): 567. CrossRef
Spontaneous Swallowing during All-Night Sleep in Patients with Parkinson Disease in Comparison with Healthy Control Subjects Irem Fatma Uludag, Bedile Irem Tiftikcioglu, Cumhur Ertekin Sleep.2016; 39(4): 847. CrossRef
Combination Technique with Ultrasonography and Electromyography for Botulinum Injection in the Cricopharyngeal Muscle: A Case Report 이상억, 심희정, 김효정, 손석일, 김민솔, 황성혜, 김병희, 허진희 Journal of the Korean Dysphagia Society.2016; 6(1): 42. CrossRef
Electrophysiological association of spontaneous yawning and swallowing Cumhur Ertekin, Nazlı Gamze Bulbul, Irem Fatma Uludag, Bedile Irem Tiftikcioglu, Sehnaz Arici, Nevin Gurgor Experimental Brain Research.2015; 233(7): 2073. CrossRef
Central cholinergic dysfunction could be associated with oropharyngeal dysphagia in early Parkinson’s disease Kyung Duck Lee, Jung Hoi Koo, Sun Hong Song, Kwang Deog Jo, Moon Kyu Lee, Wooyoung Jang Journal of Neural Transmission.2015; 122(11): 1553. CrossRef
Electrophysiological Techniques to Evaluate Swallowing in Central and Peripheral Nervous System Disorders Cumhur Ertekin Journal of Clinical Neurophysiology.2015; 32(4): 314. CrossRef
Management of oropharyngeal neurogenic dysphagia in adults Anna Miles, Jacqui E. Allen Current Opinion in Otolaryngology & Head and Neck Surgery.2015; 23(6): 433. CrossRef