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Letter to the editor
- Adult-Onset Familial TUBB4A-Related Leukodystrophy Caused by c.286G>A (p.Gly96Arg) in a Korean Family: A Case Report
- Jun Seok Lee, Sooyeoun You
- Received October 25, 2025 Accepted December 3, 2025 Published online December 10, 2025
- DOI: https://doi.org/10.14802/jmd.25285 [Epub ahead of print]
- 385 View
- 48 Download
Original Article
- Effectiveness of Live-Streaming Tele-Exercise Intervention in Patients With Parkinson’s Disease: A Pilot Study
- Jongmok Ha, Jung Hyun Park, Jun Seok Lee, Hye Young Kim, Ji One Song, Jiwon Yoo, Jong Hyeon Ahn, Jinyoung Youn, Jin Whan Cho
- J Mov Disord. 2024;17(2):189-197. Published online February 29, 2024
- DOI: https://doi.org/10.14802/jmd.23251
- 6,261 View
- 196 Download
- 7 Web of Science
- 7 Crossref
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Abstract
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Supplementary Material - Objective
Exercise can improve both motor and nonmotor symptoms in people with Parkinson’s disease (PwP), but there is an unmet need for accessible and sustainable exercise options. This study aimed to evaluate the effect, feasibility, and safety of a regularly performed live-streaming tele-exercise intervention for PwP.
Methods
A live-streaming exercise intervention for PwP was implemented twice a week for 12 weeks. We measured the motor and nonmotor symptom scores of the included patients before and after the intervention. Changes in clinical scores from baseline to postintervention were analyzed using paired t-tests. Factors associated with improvements in clinical scores and compliance were analyzed using Pearson’s correlation analysis.
Results
Fifty-six participants were enrolled in the study. There were significant improvements in Hospital Anxiety and Depression Scale (HADS)-anxiety (p = 0.007), HADS-depression (p < 0.001), Unified Parkinson’s Disease Rating Scale (UPDRS) part III (p < 0.001), UPDRS total (p = 0.015), Hoehn and Yahr stage (p = 0.027), and Parkinson’s Disease Fatigue Scale-16 (p = 0.026) scores after the intervention. Improvements in motor symptoms were associated with improvements in mood symptoms and fatigue. Higher motor impairment at baseline was associated with a greater compliance rate and better postintervention composite motor and nonmotor outcomes (ΔUPDRS total score). Overall, the 12-week tele-exercise program was feasible and safe for PwP. No adverse events were reported. The overall adherence rate was 60.0% in our cohort, and 83.4% of the participants were able to participate in more than half of the exercise routines.
Conclusion
The live-streaming tele-exercise intervention is a safe, feasible, and effective nonpharmacological treatment option that can alleviate fatigue and improve mood and motor symptoms in PwP. -
Citations
Citations to this article as recorded by
- Effects of Telehealth Interventions for People With Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Minyue Sun, Fuyou Tang, Luo min, Shiyu Wen, Shuang Wang, Huiping Jiang
JMIR mHealth and uHealth.2026; 14: e70994. CrossRef - Cycling exercise for autonomic symptoms in early Parkinson's disease
Jin-Sun Jun, Nyeonju Kang, Kiwon Park, Beomseok Jeon, Kyeongho Byun, Ryul Kim
Autonomic Neuroscience.2026; 264: 103397. CrossRef - Relationship between stigma and negative emotions among patients with Parkinson’s disease: The mediating role of health literacy and family function
Aoxue Zhu, Huiling Xie, Juan Wei, Mei Wang, Tianrong Huang, Huina Mao
Geriatric Nursing.2025; 63: 567. CrossRef - Feasibility and preliminary efficacy of an online home-based functional exercise program for Parkinson's disease: a pilot study
Hyungwoo Lee, Hunyoung Ha, Heehyun Shin, Byungjun Park, Nyeonju Kang, Kiwon Park, Ryul Kim, Kyeongho Byun
Frontiers in Neurology.2025;[Epub] CrossRef - Effectiveness of telerehabilitation in reducing motor disability and enhancing quality of life in parkinson’s disease: a systematic review and meta-analysis
Anas Zakarya Nourelden, Mohamed Mamdouh, Ibrahim Kamal, Osama Khalid Abdelgawad Ahmed, Adel Reda Abd Elwahab, Mohammed Elkholy, Abdelrahman G. Tawfik, Mohamed Hesham Gamal, Ahmed Hashem Fathallah
Acta Neurologica Belgica.2025;[Epub] CrossRef - Effects of Whole-Body, Local, and Modality-Specific Vibration Therapy on Gait in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Ji-Woo Seok, Se-Ra Park
Biomedicines.2025; 13(10): 2505. CrossRef - Factors Associated With the Response to Exercise in Patients With Parkinson’s Disease
Myung Jun Lee, Jinse Park, Dong-Woo Ryu, Dallah Yoo, Sang-Myung Cheon
Journal of Movement Disorders.2025; 18(4): 308. CrossRef
- Effects of Telehealth Interventions for People With Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Letter to the editor
- A Case of Post-Malaria Neurological Syndrome Presenting With Cortical Tremor
- Jun Seok Lee, Seongmi Kim, Jongmok Ha, Jinyoung Youn, Jin Whan Cho, Jong Hyeon Ahn
- J Mov Disord. 2024;17(1):115-117. Published online November 2, 2023
- DOI: https://doi.org/10.14802/jmd.23164
- 2,888 View
- 71 Download
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