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11 "Jinyoung Youn"
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Evaluating the Validity and Reliability of the Korean Version of the Scales for Outcomes in Parkinson’s Disease–Cognition
Jinse Park, Eungseok Oh, Seong-Beom Koh, In-Uk Song, Tae-Beom Ahn, Sang Jin Kim, Sang-Myung Cheon, Yoon-Joong Kim, Jin Whan Cho, Hyeo-Il Ma, Mee Young Park, Jong Sam Baik, Phil Hyu Lee, Sun Ju Chung, Jong-Min Kim, Han-Joon Kim, Young-Hee Sung, Do Young Kwon, Jae-Hyeok Lee, Jee-Young Lee, Ji Seon Kim, Ji Young Yun, Hee Jin Kim, Jin Yong Hong, Mi-Jung Kim, Jinyoung Youn, Hui-Jun Yang, Won Tae Yoon, Sooyeoun You, Kyum-Yil Kwon, Su-Yun Lee, Younsoo Kim, Hee-Tae Kim, Joong-Seok Kim, Ji-Young Kim
J Mov Disord. 2024;17(3):328-332.   Published online April 3, 2024
DOI: https://doi.org/10.14802/jmd.24061
  • 1,625 View
  • 87 Download
AbstractAbstract PDFSupplementary Material
Objective
The Scales for Outcomes in Parkinson’s Disease–Cognition (SCOPA-Cog) was developed to assess cognition in patients with Parkinson’s disease (PD). In this study, we aimed to evaluate the validity and reliability of the Korean version of the SCOPACog (K-SCOPA-Cog).
Methods
We enrolled 129 PD patients with movement disorders from 31 clinics in South Korea. The original version of the SCOPA-Cog was translated into Korean using the translation-retranslation method. The test–retest method with an intraclass correlation coefficient (ICC) and Cronbach’s alpha coefficient were used to assess reliability. Spearman’s rank correlation analysis with the Montreal Cognitive Assessment-Korean version (MOCA-K) and the Korean Mini-Mental State Examination (K-MMSE) were used to assess concurrent validity.
Results
The Cronbach’s alpha coefficient was 0.797, and the ICC was 0.887. Spearman’s rank correlation analysis revealed a significant correlation with the K-MMSE and MOCA-K scores (r = 0.546 and r = 0.683, respectively).
Conclusion
Our results demonstrate that the K-SCOPA-Cog has good reliability and validity.
Original Article
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Effectiveness of Live-Streaming Tele-Exercise Intervention in Patients With Parkinson’s Disease: A Pilot Study
Jongmok Ha, Jung Hyun Park, Jun Seok Lee, Hye Young Kim, Ji One Song, Jiwon Yoo, Jong Hyeon Ahn, Jinyoung Youn, Jin Whan Cho
J Mov Disord. 2024;17(2):189-197.   Published online February 29, 2024
DOI: https://doi.org/10.14802/jmd.23251
  • 2,257 View
  • 131 Download
AbstractAbstract PDFSupplementary Material
Objective
Exercise can improve both motor and nonmotor symptoms in people with Parkinson’s disease (PwP), but there is an unmet need for accessible and sustainable exercise options. This study aimed to evaluate the effect, feasibility, and safety of a regularly performed live-streaming tele-exercise intervention for PwP.
Methods
A live-streaming exercise intervention for PwP was implemented twice a week for 12 weeks. We measured the motor and nonmotor symptom scores of the included patients before and after the intervention. Changes in clinical scores from baseline to postintervention were analyzed using paired t-tests. Factors associated with improvements in clinical scores and compliance were analyzed using Pearson’s correlation analysis.
Results
Fifty-six participants were enrolled in the study. There were significant improvements in Hospital Anxiety and Depression Scale (HADS)-anxiety (p = 0.007), HADS-depression (p < 0.001), Unified Parkinson’s Disease Rating Scale (UPDRS) part III (p < 0.001), UPDRS total (p = 0.015), Hoehn and Yahr stage (p = 0.027), and Parkinson’s Disease Fatigue Scale-16 (p = 0.026) scores after the intervention. Improvements in motor symptoms were associated with improvements in mood symptoms and fatigue. Higher motor impairment at baseline was associated with a greater compliance rate and better postintervention composite motor and nonmotor outcomes (ΔUPDRS total score). Overall, the 12-week tele-exercise program was feasible and safe for PwP. No adverse events were reported. The overall adherence rate was 60.0% in our cohort, and 83.4% of the participants were able to participate in more than half of the exercise routines.
Conclusion
The live-streaming tele-exercise intervention is a safe, feasible, and effective nonpharmacological treatment option that can alleviate fatigue and improve mood and motor symptoms in PwP.
Letters to the editor
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A Case of Post-Malaria Neurological Syndrome Presenting With Cortical Tremor
Jun Seok Lee, Seongmi Kim, Jongmok Ha, Jinyoung Youn, Jin Whan Cho, Jong Hyeon Ahn
J Mov Disord. 2024;17(1):115-117.   Published online November 2, 2023
DOI: https://doi.org/10.14802/jmd.23164
  • 1,022 View
  • 49 Download
PDFSupplementary Material
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Pallidal Deep Brain Stimulation for Refractory Celiac-Related Myoclonus
Jinyoung Youn, Elizabeth Slow, Robert Chen, Andres M. Lozano, Alfonso Fasano
J Mov Disord. 2023;16(3):325-327.   Published online June 9, 2023
DOI: https://doi.org/10.14802/jmd.23006
  • 1,856 View
  • 71 Download
  • 1 Web of Science
  • 1 Crossref
PDFSupplementary Material

Citations

Citations to this article as recorded by  
  • Pallidal deep brain stimulation for patients with myoclonus-dystonia without SGCE mutations
    Jun Ikezawa, Fusako Yokochi, Ryoichi Okiyama, Ayako Isoo, Takashi Agari, Tsutomu Kamiyama, Akihiro Yugeta, Maya Tojima, Takashi Kawasaki, Katsushige Watanabe, Satoko Kumada, Kazushi Takahashi
    Journal of Neurology.2024; 271(6): 2948.     CrossRef
Orthostatic Myoclonus as a Presentation of Hashimoto Encephalopathy
Hyunyoung Hwang, Jinse Park, Jeong Ik Eun, Kyong Jin Shin, Jongmok Ha, Jinyoung Youn
J Mov Disord. 2023;16(1):104-106.   Published online January 12, 2023
DOI: https://doi.org/10.14802/jmd.22146
  • 2,307 View
  • 79 Download
  • 1 Web of Science
  • 1 Crossref
PDFSupplementary Material

Citations

Citations to this article as recorded by  
  • The use of intravenous immunoglobulin in the treatment of Hashimoto’s encephalopathy: case based review
    Victoriţa Şorodoc, Mihai Constantin, Andreea Asaftei, Cătălina Lionte, Alexandr Ceasovschih, Oana Sîrbu, Raluca Ecaterina Haliga, Laurenţiu Şorodoc
    Frontiers in Neurology.2023;[Epub]     CrossRef
Brief communication
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Validity and Reliability of the Korean-Translated Version of the International Cooperative Ataxia Rating Scale in Cerebellar Ataxia
Jinse Park, Jin Whan Cho, Jinyoung Youn, Engseok Oh, Wooyoung Jang, Joong-Seok Kim, Yoon-Sang Oh, Hyungyoung Hwang, Chang-Hwan Ryu, Jin-Young Ahn, Jee-Young Lee, Seong-Beom Koh, Jae H. Park, Hee-Tae Kim
J Mov Disord. 2023;16(1):86-90.   Published online December 20, 2022
DOI: https://doi.org/10.14802/jmd.22137
  • 2,111 View
  • 104 Download
AbstractAbstract PDFSupplementary Material
Objective
The International Cooperative Ataxia Rating Scale (ICARS) is a semiquantitative clinical scale for ataxia that is widely used in numerous countries. The purpose of this study was to investigate the validity and reliability of the Korean-translated version of the ICARS.
Methods
Eighty-eight patients who presented with cerebellar ataxia were enrolled. We investigated the construct validity using exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). We also investigated the internal consistency using Cronbach’s α and intrarater and interrater reliability using intraclass correlation coefficients.
Results
The Korean-translated ICARS showed satisfactory construct validity using EFA and CFA. It also revealed good interrater and intrarater reliability and showed acceptable internal consistency. However, subscale 4 for assessing oculomotor disorder showed moderate internal consistency.
Conclusion
This is the first report to investigate the validity and reliability of the Korean-translated ICARS. Our results showed excellent construct and convergent validity. The reliability is also acceptable.
Case Report
Successful Pallidal Stimulation in a Patient with KMT2B-Related Dystonia
Jun Kyu Mun, Ah Reum Kim, Jong Hyeon Ahn, Minkyeong Kim, Jin Whan Cho, Jung-Il Lee, Kyung Rae Cho, Jinyoung Youn
J Mov Disord. 2020;13(2):154-158.   Published online April 6, 2020
DOI: https://doi.org/10.14802/jmd.19087
  • 7,860 View
  • 179 Download
  • 13 Web of Science
  • 13 Crossref
AbstractAbstract PDFSupplementary Material
Although the KMT2B gene was identified as a causative gene for early-onset generalized dystonia, the efficacy of deep brain stimulation (DBS) in KMT2B-related dystonia has not been clearly elucidated. Here, we describe a 28-year-old woman who developed generalized dystonia with developmental delay, microcephaly, short stature, and cognitive decline. She was diagnosed with KMT2B- related dystonia using whole-exome sequencing with a heterozygous frameshift insertion of c.515dupC (p.T172fs) in the KMT2B gene. Oral medications and botulinum toxin injection were not effective. The dystonia markedly improved with bilateral pallidal DBS (the Burke-Fahn-Marsden Dystonia Rating Scale score was reduced from 30 to 5 on the dystonia movement scale and from 11 to 1 on the disability scale), and she could walk independently. From this case, we suggest that bilateral globus pallidus internus DBS can be an effective treatment option for patients with KMT2B-related generalized dystonia.

Citations

Citations to this article as recorded by  
  • The role of genetics in the treatment of dystonia with deep brain stimulation: Systematic review and Meta-analysis
    Harini Sarva, Federico Rodriguez-Porcel, Francisco Rivera, Claudio Daniel Gonzalez, Samantha Barkan, Susmit Tripathi, Emilia Gatto, Pedro Garcia Ruiz
    Journal of the Neurological Sciences.2024; 459: 122970.     CrossRef
  • GPi DBS treatment outcome in children with monogenic dystonia: a case series and review of the literature
    Darko Chudy, Marina Raguž, Vladimira Vuletić, Valentino Rački, Eliša Papić, Nataša Nenadić Baranašić, Nina Barišić
    Frontiers in Neurology.2023;[Epub]     CrossRef
  • KMT2B-Related Dystonia in Indian Patients With Literature Review and Emphasis on Asian Cohort
    Debjyoti Dhar, Vikram V Holla, Riyanka Kumari, Neeharika Sriram, Jitender Saini, Ravi Yadav, Akhilesh Pandey, Nitish Kamble, Babylakshmi Muthusamy, Pramod Kumar Pal
    Journal of Movement Disorders.2023; 16(3): 285.     CrossRef
  • Transcriptional co-activators: emerging roles in signaling pathways and potential therapeutic targets for diseases
    Priyanka Dey Talukdar, Urmi Chatterji
    Signal Transduction and Targeted Therapy.2023;[Epub]     CrossRef
  • GPi‐DBS for KMT2B‐Associated Dystonia: Systematic Review and Meta‐Analysis
    Roopa Rajan, Kanwaljeet Garg, Arti Saini, Divya M. Radhakrishnan, Miryam Carecchio, Binukumar BK, Manmohan Singh, Achal K. Srivastava
    Movement Disorders Clinical Practice.2022; 9(1): 31.     CrossRef
  • Dystonic Tremor in Adult-onset DYT-KMT2B
    Rui Shimazaki, Jun Ikezawa, Ryoichi Okiyama, Kenko Azuma, Hiroyuki Akagawa, Kazushi Takahashi
    Internal Medicine.2022; 61(15): 2357.     CrossRef
  • Dystonia type 28 with early onset (DYT-KMT2B): a clinical case
    V. A. Bulanova, M. A. Bykanova, N. А. Kuleva
    Russian Journal of Child Neurology.2022; 17(3): 79.     CrossRef
  • Identification of a novel de novo KMT2B variant in a Greek dystonia patient via exome sequencing genotype–phenotype correlations of all published cases
    Chrysoula Marogianni, Despoina Georgouli, Katerina Dadouli, Panagiotis Ntellas, Dimitrios Rikos, Georgios M. Hadjigeorgiou, Cleanthi Spanaki, Georgia Xiromerisiou
    Molecular Biology Reports.2021; 48(1): 371.     CrossRef
  • Arching deep brain stimulation in dystonia types
    Han-Joon Kim, Beomseok Jeon
    Journal of Neural Transmission.2021; 128(4): 539.     CrossRef
  • Deep Brain Stimulation for Pediatric Dystonia
    Travis Larsh, Steve W. Wu, Sudhakar Vadivelu, Gerald A. Grant, Jennifer A. O'Malley
    Seminars in Pediatric Neurology.2021; 38: 100896.     CrossRef
  • Deep Brain Stimulation in KMT2B-Related Dystonia: Case Report and Review of the Literature With Special Emphasis on Dysarthria and Speech
    Maria Abel, Robert Pfister, Iman Hussein, Fahd Alsalloum, Christina Onyinzo, Simon Kappl, Michael Zech, Walter Demmel, Martin Staudt, Manfred Kudernatsch, Steffen Berweck
    Frontiers in Neurology.2021;[Epub]     CrossRef
  • Radiofrequency ablation for DYT‐28 dystonia: short term follow‐up of three adult cases
    Shiro Horisawa, Kenkou Azuma, Hiroyuki Akagawa, Taku Nonaka, Takakazu Kawamata, Takaomi Taira
    Annals of Clinical and Translational Neurology.2020; 7(10): 2047.     CrossRef
  • KMT2B-related disorders: expansion of the phenotypic spectrum and long-term efficacy of deep brain stimulation
    Laura Cif, Diane Demailly, Jean-Pierre Lin, Katy E Barwick, Mario Sa, Lucia Abela, Sony Malhotra, Wui K Chong, Dora Steel, Alba Sanchis-Juan, Adeline Ngoh, Natalie Trump, Esther Meyer, Xavier Vasques, Julia Rankin, Meredith W Allain, Carolyn D Applegate,
    Brain.2020; 143(11): 3242.     CrossRef
Brief communication
Article image
The Effect of Globus Pallidus Interna Deep Brain Stimulation on a Dystonia Patient with the GNAL Mutation Compared to Patients with DYT1 and DYT6
Jong Hyeon Ahn, Ah Reum Kim, Nayoung K. D. Kim, Woong-Yang Park, Ji Sun Kim, Minkyeong Kim, Jongkyu Park, Jung-Il Lee, Jin Whan Cho, Kyung Rae Cho, Jinyoung Youn
J Mov Disord. 2019;12(2):120-124.   Published online May 30, 2019
DOI: https://doi.org/10.14802/jmd.19006
  • 6,715 View
  • 143 Download
  • 14 Web of Science
  • 14 Crossref
AbstractAbstract PDFSupplementary Material
Objective
The aim of this study was to investigate the efficacy of globus pallidus interna deep brain stimulation (GPi-DBS) for treating dystonia due to the GNAL mutation.
Methods
We provide the first report of a dystonia patient with a genetically confirmed GNAL mutation in the Korean population and reviewed the literature on patients with the GNAL mutation who underwent GPi-DBS. We compared the effectiveness of DBS in patients with the GNAL mutation compared to that in patients with DYT1 and DYT6 in a previous study.
Results
Patients with the GNAL mutation and those with DYT1 had higher early responder rates (GNAL, 5/5, 100%; DYT1, 7/7, 100%) than did patients with DYT6 (p = 0.047). The responder rates at late follow-up did not differ statistically among the three groups (p = 0.278). The decrease in the dystonia motor scale score in the GNAL group was 46.9% at early follow-up and 63.4% at late follow-up.
Conclusion
GPi-DBS would be an effective treatment option for dystonia patients with the GNAL mutation who are resistant to medication or botulinum toxin treatment.

Citations

Citations to this article as recorded by  
  • The role of genetics in the treatment of dystonia with deep brain stimulation: Systematic review and Meta-analysis
    Harini Sarva, Federico Rodriguez-Porcel, Francisco Rivera, Claudio Daniel Gonzalez, Samantha Barkan, Susmit Tripathi, Emilia Gatto, Pedro Garcia Ruiz
    Journal of the Neurological Sciences.2024; 459: 122970.     CrossRef
  • Pediatric Onset of Generalized Dystonia, Cognitive Impairment, and Dysmorphic Features in a Patient Carrying Compound Heterozygous GNAL Mutations
    Luca Magistrelli, Elena Contaldi, Beatrice Piola, Fjorilda Caushi, Miryam Carecchio, Sandra D'Alfonso, Lucia Corrado
    Movement Disorders Clinical Practice.2024; 11(8): 1047.     CrossRef
  • BDNF-Regulated Modulation of Striatal Circuits and Implications for Parkinson’s Disease and Dystonia
    Daniel Wolf, Maurilyn Ayon-Olivas, Michael Sendtner
    Biomedicines.2024; 12(8): 1761.     CrossRef
  • A novel GNAL pathogenic variant leading to generalized dystonia: Immediate and sustained response to globus pallidus internus deep brain stimulation
    Luigi Michele Romito, Fabio Paio, Nico Golfrè Andreasi, Celeste Panteghini, Sara Rinaldo, Ahmet Kaymak, Alberto Mazzoni, Fabiana Colucci, Vincenzo Levi, Giuseppe Messina, Barbara Garavaglia, Roberto Eleopra
    Parkinsonism & Related Disorders.2023; 115: 105833.     CrossRef
  • Applicability of clinical genetic testing for deep brain stimulation treatment in monogenic Parkinson’s disease and monogenic dystonia: a multidisciplinary team perspective
    Valentino Rački, Mario Hero, Eliša Papić, Gloria Rožmarić, Nada Starčević Čizmarević, Darko Chudy, Borut Peterlin, Vladimira Vuletić
    Frontiers in Neuroscience.2023;[Epub]     CrossRef
  • Isolated dystonia: clinical and genetic updates
    Aloysius Domingo, Rachita Yadav, Laurie J. Ozelius
    Journal of Neural Transmission.2021; 128(4): 405.     CrossRef
  • Abnormal cerebellar function and tremor in a mouse model for non‐manifesting partially penetrant dystonia type 6
    Meike E. van der Heijden, Dominic J. Kizek, Ross Perez, Elena K. Ruff, Michelle E. Ehrlich, Roy V. Sillitoe
    The Journal of Physiology.2021; 599(7): 2037.     CrossRef
  • Pallidal Deep Brain Stimulation for Monogenic Dystonia: The Effect of Gene on Outcome
    Stephen Tisch, Kishore Raj Kumar
    Frontiers in Neurology.2021;[Epub]     CrossRef
  • Arching deep brain stimulation in dystonia types
    Han-Joon Kim, Beomseok Jeon
    Journal of Neural Transmission.2021; 128(4): 539.     CrossRef
  • The Efficacy and Predictors of Using GPi-DBS to Treat Early-Onset Dystonia: An Individual Patient Analysis
    Wenxiu Chen, Houyou Fan, Guohui Lu, Fushun Wang
    Neural Plasticity.2021; 2021: 1.     CrossRef
  • Deep brain stimulation in dystonia: State of art and future directions
    A. Macerollo, V. Sajin, M. Bonello, D. Barghava, S. H Alusi, P. R Eldridge, J. Osman-Farah
    Journal of Neuroscience Methods.2020; 340: 108750.     CrossRef
  • Successful Pallidal Stimulation in a Patient with KMT2B-Related Dystonia
    Jun Kyu Mun, Ah Reum Kim, Jong Hyeon Ahn, Minkyeong Kim, Jin Whan Cho, Jung-Il Lee, Kyung Rae Cho, Jinyoung Youn
    Journal of Movement Disorders.2020; 13(2): 154.     CrossRef
  • Clinical characteristics of ataxia-telangiectasia presenting dystonia as a main manifestation
    Minkyeong Kim, Ah Reum Kim, Jongkyu Park, Ji Sun Kim, Jong Hyeon Ahn, Woong-Yang Park, Nayoung K.D. Kim, Chung Lee, Nam-Soon Kim, Jin Whan Cho, Jinyoung Youn
    Clinical Neurology and Neurosurgery.2020; 199: 106267.     CrossRef
  • Reply to: The Spectrum of Movement Disorders in 18p Deletion Syndrome
    David Crosiers, Bettina Blaumeiser, Gert Van Goethem
    Movement Disorders Clinical Practice.2019; 6(8): 731.     CrossRef
Original Articles
Article image
Validity and Reliability Study of the Korean Tinetti Mobility Test for Parkinson’s Disease
Jinse Park, Seong-Beom Koh, Hee Jin Kim, Eungseok Oh, Joong-Seok Kim, Ji Young Yun, Do-Young Kwon, Younsoo Kim, Ji Seon Kim, Kyum-Yil Kwon, Jeong-Ho Park, Jinyoung Youn, Wooyoung Jang
J Mov Disord. 2018;11(1):24-29.   Published online January 23, 2018
DOI: https://doi.org/10.14802/jmd.17058
  • 12,458 View
  • 275 Download
  • 14 Web of Science
  • 14 Crossref
AbstractAbstract PDFSupplementary Material
Objective
Postural instability and gait disturbance are the cardinal symptoms associated with falling among patients with Parkinson’s disease (PD). The Tinetti mobility test (TMT) is a well-established measurement tool used to predict falls among elderly people. However, the TMT has not been established or widely used among PD patients in Korea. The purpose of this study was to evaluate the reliability and validity of the Korean version of the TMT for PD patients.
Methods
Twenty-four patients diagnosed with PD were enrolled in this study. For the interrater reliability test, thirteen clinicians scored the TMT after watching a video clip. We also used the test-retest method to determine intrarater reliability. For concurrent validation, the unified Parkinson’s disease rating scale, Hoehn and Yahr staging, Berg Balance Scale, Timed-Up and Go test, 10-m walk test, and gait analysis by three-dimensional motion capture were also used. We analyzed receiver operating characteristic curve to predict falling.
Results
The interrater reliability and intrarater reliability of the Korean Tinetti balance scale were 0.97 and 0.98, respectively. The interrater reliability and intra-rater reliability of the Korean Tinetti gait scale were 0.94 and 0.96, respectively. The Korean TMT scores were significantly correlated with the other clinical scales and three-dimensional motion capture. The cutoff values for predicting falling were 14 points (balance subscale) and 10 points (gait subscale).
Conclusion
We found that the Korean version of the TMT showed excellent validity and reliability for gait and balance and had high sensitivity and specificity for predicting falls among patients with PD.

Citations

Citations to this article as recorded by  
  • Validity and Reliability of the Korean-Translated Version of the International Cooperative Ataxia Rating Scale in Cerebellar Ataxia
    Jinse Park, Jin Whan Cho, Jinyoung Youn, Engseok Oh, Wooyoung Jang, Joong-Seok Kim, Yoon-Sang Oh, Hyungyoung Hwang, Chang-Hwan Ryu, Jin-Young Ahn, Jee-Young Lee, Seong-Beom Koh, Jae H. Park, Hee-Tae Kim
    Journal of Movement Disorders.2023; 16(1): 86.     CrossRef
  • Reliability and validity of the Tinetti performance oriented mobility assessment in Chinese community-dwelling older adults
    Chen Yang, Yihan Mo, Xi Cao, Song Zhu, Xiuhua Wang, Xiaoqing Wang
    Geriatric Nursing.2023; 53: 85.     CrossRef
  • Validation of the Performance Oriented Mobility Assessment (Tinetti Test) Scale in Russia for Stroke Patients
    Elena V. Kostenko, Liudmila V. Petrova, Irena V. Pogonchenkova
    Bulletin of Rehabilitation Medicine.2023; 22(3): 29.     CrossRef
  • Dance Intervention Using the Feldenkrais Method Improves Motor, and Non-Motor Symptoms and Gait in Parkinson’s Disease: A 12-Month Study
    Sung Hoon Kang, Jinhee Kim, Ilsoo Kim, Young Ae Moon, Sojung Park, Seong-Beom Koh
    Journal of Movement Disorders.2022; 15(1): 53.     CrossRef
  • Performance-Oriented Mobility Assessment test and Timed Up and Go test as predictors of falls in the elderly – A cross-sectional study
    Varatharajan Sakthivadivel, Jeganathan Geetha, Archana Gaur, Ariyanachi Kaliappan
    Journal of Family Medicine and Primary Care.2022; 11(11): 7294.     CrossRef
  • Evaluation of Anticipatory Postural Adjustment before Quantified Weight Shifting—System Development and Reliability Test
    Jiunn-Woei Liaw, Rou-Shayn Chen, Vincent Chiun-Fan Chen, Yan-Ru Wang, Hsiao-Lung Chan, Ya-Ju Chang
    Applied Sciences.2021; 11(2): 758.     CrossRef
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    Jan Neugebauer, Valérie Tóthová, Jitka Doležalová
    International Journal of Environmental Research and Public Health.2021; 18(6): 3226.     CrossRef
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    Kyong Jin Shin, Jinse Park, Samyeol Ha, Kang Min Park, Sung Eun Kim, Byung In Lee, Dong Ah Lee, Hee-Tae Kim, Ji-Yeon Yoon
    Gait & Posture.2020; 76: 64.     CrossRef
  • Design of a Machine Learning-Assisted Wearable Accelerometer-Based Automated System for Studying the Effect of Dopaminergic Medicine on Gait Characteristics of Parkinson’s Patients
    Satyabrata Aich, Pyari Mohan Pradhan, Sabyasachi Chakraborty, Hee-Cheol Kim, Hee-Tae Kim, Hae-Gu Lee, Il Hwan Kim, Moon-il Joo, Sim Jong Seong, Jinse Park
    Journal of Healthcare Engineering.2020; 2020: 1.     CrossRef
  • Psychometric properties and domains of postural control tests for individuals with knee osteoarthritis: a systematic review
    Helen P. French, Charlotte K. Hager, Anne Venience, Ryan Fagan, Dara Meldrum
    International Journal of Rehabilitation Research.2020; 43(2): 102.     CrossRef
  • Measures of balance and falls risk prediction in people with Parkinson’s disease: a systematic review of psychometric properties
    Stanley J Winser, Priya Kannan, Umar Muhhamad Bello, Susan L Whitney
    Clinical Rehabilitation.2019; 33(12): 1949.     CrossRef
  • Allelic variant in SLC6A3 rs393795 affects cerebral regional homogeneity and gait dysfunction in patients with Parkinson’s disease
    Lina Wang, Yongsheng Yuan, Jianwei Wang, Yuting Shen, Yan Zhi, Junyi Li, Min Wang, Kezhong Zhang
    PeerJ.2019; 7: e7957.     CrossRef
  • Evaluation of Balance Disorders in Parkinson's Disease Using Simple Diagnostic Tests—Not So Simple to Choose
    Karolina Krzysztoń, Jakub Stolarski, Jan Kochanowski
    Frontiers in Neurology.2018;[Epub]     CrossRef
  • Rasch Analysis of the Clinimetric Properties of the Korean Dizziness Handicap Inventory in Patients with Parkinson Disease
    Da-Young Lee, Hui-Jun Yang, Dong-Seok Yang, Jin-Hyuk Choi, Byoung-Soo Park, Ji-Yun Park
    Research in Vestibular Science.2018; 17(4): 152.     CrossRef
Validation of the Korean Version of the Scale for Outcomes in Parkinson’s Disease-Autonomic
Ji-Young Kim, In-Uk Song, Seong-Beom Koh, Tae-Beom Ahn, Sang Jin Kim, Sang-Myung Cheon, Jin Whan Cho, Yun Joong Kim, Hyeo-Il Ma, Mee-Young Park, Jong Sam Baik, Phil Hyu Lee, Sun Ju Chung, Jong-Min Kim, Han-Joon Kim, Young-Hee Sung, Do Young Kwon, Jae-Hyeok Lee, Jee-Young Lee, Ji Sun Kim, Ji Young Yun, Hee Jin Kim, Jin Young Hong, Mi-Jung Kim, Jinyoung Youn, Ji Seon Kim, Eung Seok Oh, Hui-Jun Yang, Won Tae Yoon, Sooyeoun You, Kyum-Yil Kwon, Hyung-Eun Park, Su-Yun Lee, Younsoo Kim, Hee-Tae Kim, Joong-Seok Kim
J Mov Disord. 2017;10(1):29-34.   Published online January 18, 2017
DOI: https://doi.org/10.14802/jmd.16057
  • 16,193 View
  • 375 Download
  • 31 Web of Science
  • 33 Crossref
AbstractAbstract PDFSupplementary Material
Objective
Autonomic symptoms are commonly observed in patients with Parkinson’s disease (PD) and often limit the activities of daily living. The Scale for Outcomes in Parkinson’s disease-Autonomic (SCOPA-AUT) was developed to evaluate and quantify autonomic symptoms in PD. The goal of this study was to translate the original SCOPA-AUT, which was written in English, into Korean and to evaluate its reliability and validity for Korean PD patients.
Methods
For the translation, the following processes were performed: forward translation, backward translation, expert review, pretest of the pre-final version and development of the final Korean version of SCOPA-AUT (K-SCOPA-AUT). In total, 127 patients with PD from 31 movement disorder clinics of university-affiliated hospitals in Korea were enrolled in this study. All patients were assessed using the K-SCOPA-AUT and other motor, non-motor, and quality of life scores. Test-retest reliability for the K-SCOPA-AUT was assessed over a time interval of 10−14 days.
Results
The internal consistency and reliability of the K-SCOPA-AUT was 0.727 as measured by the mean Cronbach’s α-coefficient. The test-retest correlation reliability was 0.859 by the Guttman split-half coefficient. The total K-SCOPA-AUT score showed a positive correlation with other non-motor symptoms [the Korean version of non-motor symptom scale (K-NMSS)], activities of daily living (Unified Parkinson’s Disease Rating Scale part II) and quality of life [the Korean version of Parkinson’s Disease Quality of Life 39 (K-PDQ39)].
Conclusion
The K-SCOPA-AUT had good reliability and validity for the assessment of autonomic dysfunction in Korean PD patients. Autonomic symptom severities were associated with many other motor and non-motor impairments and influenced quality of life.

Citations

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Preliminary Study of Intravenous Amantadine Treatment for Ataxia Management in Patients with Probable Multiple System Atrophy with Predominant Cerebellar Ataxia
Jinyoung Youn, Hyeeun Shin, Ji Sun Kim, Jin Whan Cho
J Mov Disord. 2012;5(1):1-4.
DOI: https://doi.org/10.14802/jmd.12001
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AbstractAbstract PDF
Background and Purpose:

Multiple system atrophy with predominant cerebellar ataxia is a disabling neurologic disease. However, effective management has not yet been established. We conducted a short-term, open-label preliminary study to assess the benefits of intravenous amantadine treatment in patients with probable multiple system atrophy with predominant cerebellar ataxia.

Methods:

Twenty patients (10 male, 10 female) with probable multiple system atrophy with predominant cerebellar ataxia received 400 mg of amantadine by intravenous per day for 5 days. Ataxia severity was evaluated by the International Cooperative Ataxia Rating Scale before and after intravenous amantadine therapy and all subjects reported subjective improvement after intravenous amantadine treatment using a patient global impression scale. We analyzed the total and subscale scores by the ataxia scale and patient global impression scale.

Results:

The mean age was 57.4 years (range: 47–72) and the mean disease duration was 30.8 months (range: 11–79). The ataxia severity significantly decreased after intravenous amantadine therapy from 42.5 to 37.3 (p < 0.001). The mean patient global impression scale for improvement was 2.9 and there were no side effects of intravenous amantadine treatment observed. When we assessed responders, the duration of intravenous amantadine effect was more than 1 month in 4 subjects of 7 responders.

Conclusions:

Our findings suggest that intravenous amantadine treatment can be a safe management option in cerebellar ataxia, although the mechanism is unclear. Thus, further double-blind, long-term studies with a larger sample size are needed.

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