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- Creutzfeldt-Jakob Disease in a Tertiary Care Hospital in Thailand: A Case Series and Review of the Literature
- Praween Lolekha, Ahmed Rasheed, Chutanat Yotsarawat
- J Mov Disord. 2015;8(3):136-140. Published online September 10, 2015
- DOI: https://doi.org/10.14802/jmd.15014
- 22,037 View
- 98 Download
- 11 Web of Science
- 9 Crossref
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Abstract
PDF - Creutzfeldt-Jakob Disease (CJD) is an incurable and inevitably fatal neurodegenerative disorder. Although CJD has a worldwide distribution, there are no official statistics on CJD in Thailand. A diagnosis of CJD is suspected when a patient develops rapidly progressive dementia with myoclonus. However, CJD may be mistaken for a variety of illnesses because its initial presentation frequently consists of non-specific symptoms. Here, we examined cases of sporadic CJD (sCJD) from Thammasat University Hospital (a tertiary care hospital in Thailand) between January 1, 2012 and December 31, 2014. Three cases of probable and possible sCJD were collected. All cases presented with rapidly progressive cognitive dysfunction accompanied by spontaneous myoclonus. Classical electroencehalography changes and typical abnormal MRI features were observed. All of the cases died within a period of 8 months. None of the patients underwent brain biopsy. Our findings raise questions about the prevalence of CJD in Thailand, which needs further study.
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Citations
Citations to this article as recorded by
- Clinical Manifestations of Sporadic Creutzfeldt-Jakob Disease in a Public Neurological Hospital in Thailand
Jedsada Khieukhajee, Arada Rojana-udomsart
Alzheimer Disease & Associated Disorders.2025; 39(2): 117. CrossRef - Sporadic Creutzfeldt-Jakob disease: Brain MRI lesion features from 2 cases reports
Hoang Dinh Au, Nguyen Thu Lan, Nguyen Thai Binh, Le Tuan Linh, Ma Mai Hien, Nguyen Minh Duc
Radiology Case Reports.2024; 19(3): 939. CrossRef - A systemic analysis of Creutzfeldt Jakob disease cases in Asia
Urwah Rasheed, Sana Khan, Minahil Khalid, Aneeqa Noor, Saima Zafar
Prion.2024; 18(1): 11. CrossRef - Updated global epidemiology atlas of human prion diseases
Li-Ping Gao, Ting-Ting Tian, Kang Xiao, Cao Chen, Wei Zhou, Dong-Lin Liang, Run-Dong Cao, Qi Shi, Xiao-Ping Dong
Frontiers in Public Health.2024;[Epub] CrossRef - Characteristics of Creutzfeldt-Jakob disease at Siriraj Hospital, Thailand: Case series and literature review
Chaisak Dumrikarnlert, Nuttapong Kanokkawinwong, Chatchawan Rattanabannakit, Vorapun Senanarong
Clinical Parkinsonism & Related Disorders.2024; 11: 100281. CrossRef - The importance of ongoing international surveillance for Creutzfeldt–Jakob disease
Neil Watson, Jean-Philippe Brandel, Alison Green, Peter Hermann, Anna Ladogana, Terri Lindsay, Janet Mackenzie, Maurizio Pocchiari, Colin Smith, Inga Zerr, Suvankar Pal
Nature Reviews Neurology.2021; 17(6): 362. CrossRef - Case series of Creutzfeldt-Jakob disease in a third-level hospital in Quito
Germaine Eleanor Torres Herrán, Andrés Damián Ortega Herrera, Braulio Martinez Burbano, Marcos Serrano-Dueñas, María Angélica Ortiz Yepez, Raúl Alberto Barrera Madera, Luis Alfredo Masabanda Campaña, Guillermo David Baño Jiménez, Denny Maritza Santos Salt
BMC Neurology.2018;[Epub] CrossRef - An Evaluation of Rapidly Progressive Dementia Culminating in a Diagnosis of Creutzfeldt–Jakob Disease
Parmvir Parmar, Curtis L. Cooper, Daniel Kobewka
Case Reports in Infectious Diseases.2018; 2018: 1. CrossRef - Diffusion-weighted MRI abnormalities antedate the onset of sporadic Creutzfeldt-Jakob disease
Keisuke Suzuki, Akiko Kawasaki, Takahide Nagashima, Koichi Hirata
Neurology.2016; 87(8): 843. CrossRef
- Clinical Manifestations of Sporadic Creutzfeldt-Jakob Disease in a Public Neurological Hospital in Thailand
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