- Thalamic deep brain stimulation for SPG-56 related focal hand dystonia
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Momo Uchida, Shiro Horisawa, Kenkou Azuma, Hiroyuki Akagawa, Shinichi Tokushige, Takakazu Kawamata, Takaomi Taira
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Received January 27, 2024 Accepted June 26, 2024 Published online June 27, 2024
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DOI: https://doi.org/10.14802/jmd.24022
[Accepted]
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- Efficacy and safety of zolpidem for musician’s dystonia
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Shiro Horisawa, Kilsoo Kim, Masato Murakami, Masahiko Nishitani, Takakazu Kawamata, Takaomi Taira
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Received May 20, 2024 Accepted June 28, 2024 Published online July 1, 2024
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DOI: https://doi.org/10.14802/jmd.24121
[Accepted]
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 Abstract
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- Background
The efficacy and safety of zolpidem in treating musician’s dystonia are not well understood.
Objective
We aimed to retrospectively investigate the efficacy and safety of zolpidem for musician’s dystonia.
Methods
We retrospectively reviewed medical records between January 2021 and December 2023 to identify patients with musician’s dystonia who had been prescribed zolpidem. The Tubiana’s musician’s dystonia rating scale (range, 1-5; lower scores indicating greater severity) was used to evaluate musician’s dystonia.
Results
Fifteen patients were included in this study. The mean effective dose of zolpidem was 5.3±2.0 mg. The mean effective duration of zolpidem was 4.3±1.2 h. With zolpidem administration, the Tubiana’s musician’s dystonia rating scale score significantly improved from 2.2±1.0 to 4.3±0.8 (48.9% improvement, p<0.001). Two patients (13.3%) discontinued the drug owing to unsatisfactory results or sleepiness.
Conclusion
This study suggests that zolpidem may be an alternative treatment option for musician’s dystonia.
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