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JMD : Journal of Movement Disorders


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Sook-Keun Song 1 Article
Unilateral Standing Leg Tremor as the Initial Manifestation of Parkinson Disease
Suk Yun Kang, Sook-Keun Song, Jin-Soo Kim, Young Ho Sohn
J Mov Disord. 2009;2(1):29-32.
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AbstractAbstract PDF

The aim of this study was to analyze the different forms of leg tremors exhibited while standing in patients with Parkinson disease (PD), and to determine if the type of leg tremor exhibited is indicative of prognosis or treatment response in PD patients.


We studied the clinical characteristics of five PD patients (all women; mean age, 59 years, range, 53–64 years) with unilateral standing leg tremor as the initial manifestation of PD, including their electrophysiological findings and the results of long-term follow-up.


For each patient, parkinsonism either existed at the time of onset of the initial symptoms or developed later. Patient responses to drugs were generally good, but one patient showed a poor response to drugs, even though she had only a low frequency leg tremor. For two patients whom we could observe during the 10-year follow-up period, neither the leg tremor nor parkinsonism was aggravated.


There are two forms of unilateral standing leg tremor in PD. One form is high frequency, similar to the primary orthostatic tremor. The other is low frequency and similar to the parkinsonian resting tremor. Based on these observations, it appears that progression might be slow if PD patients have standing leg tremor as the initial manifestation.


Citations to this article as recorded by  
  • Orthostatic tremor as initial presentation of Parkinson’s disease
    Y R Chiew
    QJM: An International Journal of Medicine.2023; 116(7): 549.     CrossRef
  • The ‘Postural Rhythm’ of the Ground Reaction Force during Upright Stance and Its Conversion to Body Sway—The Effect of Vision, Support Surface and Adaptation to Repeated Trials
    Stefania Sozzi, Shashank Ghai, Marco Schieppati
    Brain Sciences.2023; 13(7): 978.     CrossRef
  • An unusual initial presentation of Parkinson’s disease: unilateral standing leg tremor
    Jasem Yousef Al-Hashel, Walaa Ahmed Kamel, Philippe Damier, Ahmad Jasem Abdulsalam
    Acta Neurologica Belgica.2020; 120(2): 415.     CrossRef

JMD : Journal of Movement Disorders