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Jae Wook Cho 2 Articles
Spinocerebellar Ataxia 13 Presenting with Pure Cerebellar Syndrome in a Korean Family
Minkyeong Kim, Seung Hwan Oh, Jae Wook Cho, Jae-Hyeok Lee
J Mov Disord. 2020;13(3):244-246.   Published online September 9, 2020
DOI: https://doi.org/10.14802/jmd.20064
  • 3,032 View
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Suppression of Myoclonus in Corticobasal Degeneration by Levetiracetam
Jae Wook Cho, Jae Hyeok Lee
J Mov Disord. 2014;7(1):28-30.   Published online April 30, 2014
DOI: https://doi.org/10.14802/jmd.14007
  • 8,844 View
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  • 10 Citations
AbstractAbstract PDF
Myoclonus in corticobasal degeneration (CBD) has often been associated with severe and difficult to treat disabilities. Levetiracetam is a new antiepileptic agent with antimyoclonic effects. Herein, we present a 72-year-old woman with clinically probable CBD and with spontaneous rhythmic myoclonus in the right foot, which was markedly ameliorated through treatment with levetiracetam. The effect of levetiracetam was associated with the decreased amplitude of enlarged cortical somatosensory evoked potentials. This result suggests that the antimyoclonic effect of levetiracetam might be mediated through the suppression of increased cortical excitability.

JMD : Journal of Movement Disorders