Journal of Movement Disorders

Hyeo-Il Ma

11 Articles

Olfactory and Gustatory Function in Early-Stage Parkinson’s Disease: Implications for Cognitive Association: Jeongjae Lee, Young Eun Kim, Joong Seob Lee, Suk Yun Kang, Min Seung Kim, In Hee Kwak, Jaeseol Park, Jung Yeon Nam, Hyeo-il Ma; J Mov Disord. 2024;17(4):450-452. Published online June 27, 2024; DOI: https://doi.org/10.14802/jmd.23243

1,193 View
70 Download

PDF Supplementary Material

Evaluating the Validity and Reliability of the Korean Version of the Scales for Outcomes in Parkinson’s Disease–Cognition: Jinse Park, Eungseok Oh, Seong-Beom Koh, In-Uk Song, Tae-Beom Ahn, Sang Jin Kim, Sang-Myung Cheon, Yoon-Joong Kim, Jin Whan Cho, Hyeo-Il Ma, Mee Young Park, Jong Sam Baik, Phil Hyu Lee, Sun Ju Chung, Jong-Min Kim, Han-Joon Kim, Young-Hee Sung, Do Young Kwon, Jae-Hyeok Lee, Jee-Young Lee, Ji Seon Kim, Ji Young Yun, Hee Jin Kim, Jin Yong Hong, Mi-Jung Kim, Jinyoung Youn, Hui-Jun Yang, Won Tae Yoon, Sooyeoun You, Kyum-Yil Kwon, Su-Yun Lee, Younsoo Kim, Hee-Tae Kim, Joong-Seok Kim, Ji-Young Kim; J Mov Disord. 2024;17(3):328-332. Published online April 3, 2024; DOI: https://doi.org/10.14802/jmd.24061

2,118 View
106 Download

Abstract PDF Supplementary Material: Objective
The Scales for Outcomes in Parkinson’s Disease–Cognition (SCOPA-Cog) was developed to assess cognition in patients with Parkinson’s disease (PD). In this study, we aimed to evaluate the validity and reliability of the Korean version of the SCOPACog (K-SCOPA-Cog).
Methods
We enrolled 129 PD patients with movement disorders from 31 clinics in South Korea. The original version of the SCOPA-Cog was translated into Korean using the translation-retranslation method. The test–retest method with an intraclass correlation coefficient (ICC) and Cronbach’s alpha coefficient were used to assess reliability. Spearman’s rank correlation analysis with the Montreal Cognitive Assessment-Korean version (MOCA-K) and the Korean Mini-Mental State Examination (K-MMSE) were used to assess concurrent validity.
Results
The Cronbach’s alpha coefficient was 0.797, and the ICC was 0.887. Spearman’s rank correlation analysis revealed a significant correlation with the K-MMSE and MOCA-K scores (r = 0.546 and r = 0.683, respectively).
Conclusion
Our results demonstrate that the K-SCOPA-Cog has good reliability and validity.

Comparative Olfactory Profiles in Parkinson’s Disease and Drug-Induced Parkinsonism: In Hee Kwak, Young Eun Kim, Suk Yun Kang, Joong Seob Lee, Jeongjae Lee, Min Seung Kim, Dong A Yea, Hyeo-il Ma; J Mov Disord. 2024;17(1):64-70. Published online October 6, 2023; DOI: https://doi.org/10.14802/jmd.23105

2,355 View
453 Download
1 Web of Science
1 Crossref

Abstract PDF Supplementary Material

Objective
Drug-induced parkinsonism (DIP) is a frequently encountered diagnostic possibility when considering Parkinson’s disease (PD). While olfactory dysfunction is a common clinical feature in PD, the comparison of olfactory function between the two conditions remains insufficient. This study aimed to compare olfactory function, including threshold, discrimination, and identification (TDI) profiles, between PD and DIP.
Methods
Consecutive patients with drug-naïve PD (n = 78) or DIP (n = 31) confirmed through dopamine transporter imaging were enrolled in this study. The YSK olfactory function (YOF) test, composed of TDI domains culturally familiar odorants to Koreans, was administered to all patients.
Results
In the study population, patients with DIP were significantly older than patients with PD. Over 70% of patients in each group had hyposmia or anosmia, and there was no significant difference in the occurrence of olfactory dysfunction between the two groups. In addition, there were no differences in the total YOF score and threshold score between the two groups. Meanwhile, the PD group had a significantly lower discrimination and identification score than the DIP group after adjusting for age, sex, the existence of diabetes, disease duration, and cognitive function.
Conclusion
This study demonstrated that detailed olfactory profiles are different in PD and DIP, even though olfactory dysfunction can be observed in both conditions.

Citations

Citations to this article as recorded by

Olfactory dysfunction as potential biomarker in neurodegenerative diseases: a narrative review
Nicolas De Cleene, Katarína Schwarzová, Samuel Labrecque, Clancy Cerejo, Atbin Djamshidian, Klaus Seppi, Beatrice Heim
Frontiers in Neuroscience.2025;[Epub] CrossRef

Evidence of Inflammation in Parkinson’s Disease and Its Contribution to Synucleinopathy: Thuy Thi Lai, Yun Joong Kim, Hyeo-il Ma, Young Eun Kim; J Mov Disord. 2022;15(1):1-14. Published online November 3, 2021; DOI: https://doi.org/10.14802/jmd.21078

10,000 View
587 Download
17 Web of Science
18 Crossref

Abstract PDF

Accumulation of alpha-synuclein (αSyn) protein in neurons is a renowned pathological hallmark of Parkinson’s disease (PD). In addition, accumulating evidence indicates that activated inflammatory responses are involved in the pathogenesis of PD. Thus, achieving a better understanding of the interaction between inflammation and synucleinopathy in relation to the PD process will facilitate the development of promising disease-modifying therapies. In this review, the evidence of inflammation in PD is discussed, and human, animal, and laboratory studies relevant to the relationship between inflammation and αSyn are explored as well as new therapeutic targets associated with this relationship.

Citations

Citations to this article as recorded by

Roflumilast attenuates doxorubicin and cyclophosphamide combination-induced chemobrain in rats through modulation of NLRP3/ASC/caspase-1/GSDMD axis
Georgette Eskander, Sherihan G. Abdelhamid, Sara A. Wahdan, Sara M. Radwan
Life Sciences.2025; 362: 123378. CrossRef
The Systemic Immune-Inflammation Index and the Risk of Parkinson’s Disease in the U.S.: A Cross-Sectional Study
Fujun Liu, Qibo Ran, Huajin Zhang, Jing Chen
Journal of Clinical Medicine.2025; 14(2): 403. CrossRef
Recent advances of nanomaterials for intervention in Parkinson’s disease in the context of anti-inflammation
Ruoyu Zhang, Xiaotong Chen, Yuanyuan Cheng, Zixuan Chen, Xiaoqiong Li, Yulin Deng
Coordination Chemistry Reviews.2024; 502: 215616. CrossRef
Microglial inhibition alleviates alpha-synuclein propagation and neurodegeneration in Parkinson’s disease mouse model
Thuy Thi Lai, Young Eun Kim, Linh Thi Nhat Nguyen, Tinh Thi Nguyen, In Hee Kwak, Franziska Richter, Yun Joong Kim, Hyeo-il Ma
npj Parkinson's Disease.2024;[Epub] CrossRef
New Insights into Oxidative Stress and Inflammatory Response in Neurodegenerative Diseases
Eveljn Scarian, Camilla Viola, Francesca Dragoni, Rosalinda Di Gerlando, Bartolo Rizzo, Luca Diamanti, Stella Gagliardi, Matteo Bordoni, Orietta Pansarasa
International Journal of Molecular Sciences.2024; 25(5): 2698. CrossRef
Neuroinflammation following anti-parkinsonian drugs in early Parkinson’s disease: a longitudinal PET study
Tatsuhiro Terada, Tomoyasu Bunai, Takanori Hashizume, Takashi Matsudaira, Masamichi Yokokura, Hirotsugu Takashima, Takashi Konishi, Tomokazu Obi, Yasuomi Ouchi
Scientific Reports.2024;[Epub] CrossRef
The effect of crocin on movement disorders and oxidative DNA damage in Parkinson's disease: Insights from a randomized controlled trial
Saeed Mohammad Soleymani, Farhad Assarzadegan, Seyed Amir Hassan Habibi, Arash Mahboubi, Hadi Esmaily
Parkinsonism & Related Disorders.2024; 126: 107051. CrossRef
Atractylenolide-I Ameliorates Motor Deficits and Reduces Inflammation of the Spinal Cord by SIRT1/PGC-1α Pathway in MPTP Subacute Mouse Model of Parkinson’s Disease
Ya Gao, Shuyue Li, Jian Zhang, Yidan Zhang, Yuan Zhao, Shuming Zhang, Lujie Zuo, Guofeng Yang
Neuropsychiatric Disease and Treatment.2024; Volume 20: 1919. CrossRef
Parkinson’s disease is associated with clonal hematopoiesis with TET2 mutation
Kyung Ah Woo, Han-Joon Kim, Chan Young Lee, Jung Hwan Shin, Choonghyun Sun, Hogune Im, Hongyul An, Jiwoo Lim, Su-Yeon Choi, Youngil Koh, Beomseok Jeon
npj Parkinson's Disease.2024;[Epub] CrossRef
Neuroinflammation and Immune Dysfunction in the Mechanisms of Development of Parkinson’s Disease
G. V. Idova, E. L. Alperina, S. Ya. Zhanaeva
Neuroscience and Behavioral Physiology.2023; 53(9): 1534. CrossRef
Vitamin D3 actions on astrocyte cells: A target for therapeutic strategy in Parkinson’s disease?
Erlânia Alves de Siqueira, Emanuel Paula Magalhães, Ramon Róseo Paula Pessoa Bezerra de Menezes, Tiago Lima Sampaio, Danya Bandeira Lima, Conceição da Silva Martins, Kelly Rose Tavares Neves, Gerly Anne de Castro Brito, Alice Maria Costa Martins, Glauce S
Neuroscience Letters.2023; 793: 136997. CrossRef
ASC specks exacerbate α‑synuclein pathology via amplifying NLRP3 inflammasome activities
Ran Zheng, Yiqun Yan, Shaobing Dai, Yang Ruan, Ying Chen, Chenjun Hu, Zhihao Lin, Naijia Xue, Zhe Song, Yi Liu, Baorong Zhang, Jiali Pu
Journal of Neuroinflammation.2023;[Epub] CrossRef
NLRP3 Inflammasome-Mediated Neuroinflammation and Related Mitochondrial Impairment in Parkinson’s Disease
Qiu-Qin Han, Weidong Le
Neuroscience Bulletin.2023; 39(5): 832. CrossRef
The Role of Ubiquitin–Proteasome System and Mitophagy in the Pathogenesis of Parkinson's Disease
Yu Liang, Guangshang Zhong, Mingxin Ren, Tingting Sun, Yangyang Li, Ming Ye, Caiyun Ma, Yu Guo, Changqing Liu
NeuroMolecular Medicine.2023; 25(4): 471. CrossRef
Anethole attenuates motor dysfunctions, striatal neuronal activity deficiency and blood brain barrier permeability by decreasing striatal α-synuclein and oxidative stress in rotenone-induced Parkinson’s disease of male rats
Sadegh Moradi Vastegani, Seyed Esmaeil Khoshnam, Samireh Ghafouri, Nima Bakhtiari, Yaghoob Farbood, Alireza Sarkaki, Wesley Lyeverton Correia Ribeiro
PLOS ONE.2023; 18(11): e0294612. CrossRef
NEUROINFLAMMATION AND IMMUNE DYSFUNCTION IN THE PATHOGENESIS OF PARKINSON’S DISEASE
G. V. Idova, E. L. Alperina, S. Ya. Zhanaeva
Журнал высшей нервной деятельности им. И.П. Павлова.2023; 73(4): 454. CrossRef
A2A Adenosine Receptor Antagonists: Are Triazolotriazine and Purine Scaffolds Interchangeable?
Andrea Spinaci, Catia Lambertucci, Michela Buccioni, Diego Dal Ben, Claudia Graiff, Maria Cristina Barbalace, Silvana Hrelia, Cristina Angeloni, Seyed Khosrow Tayebati, Massimo Ubaldi, Alessio Masi, Karl-Norbert Klotz, Rosaria Volpini, Gabriella Marucci
Molecules.2022; 27(8): 2386. CrossRef
Oligomeropathies, inflammation and prion protein binding
Gianluigi Forloni, Pietro La Vitola, Claudia Balducci
Frontiers in Neuroscience.2022;[Epub] CrossRef

Presynaptic Dopaminergic Degeneration in a Patient with Beta-Propeller Protein-Associated Neurodegeneration Documented by Dopamine Transporter Positron Emission Tomography Images: A Case Report: Min Ki Kim, Nan Young Kim, Sangkyoon Hong, Hyeo-Il Ma, Yun Joong Kim; J Mov Disord. 2017;10(3):161-163. Published online September 12, 2017; DOI: https://doi.org/10.14802/jmd.17044

5,964 View
96 Download
2 Web of Science
3 Crossref

PDF

Citations

Citations to this article as recorded by

Comprehensive analysis of autophagic functions of WIPI family proteins and their implications for the pathogenesis of β-propeller associated neurodegeneration
Takahiro Shimizu, Norito Tamura, Taki Nishimura, Chieko Saito, Hayashi Yamamoto, Noboru Mizushima
Human Molecular Genetics.2023; 32(16): 2623. CrossRef
Interactions of dopamine, iron, and alpha-synuclein linked to dopaminergic neuron vulnerability in Parkinson's disease and Neurodegeneration with Brain Iron Accumulation disorders
Rachel M. Wise, Annika Wagener, Urban M. Fietzek, Thomas Klopstock, Eugene V. Mosharov, Fabio A. Zucca, David Sulzer, Luigi Zecca, Lena F. Burbulla
Neurobiology of Disease.2022; 175: 105920. CrossRef
WDR45, one gene associated with multiple neurodevelopmental disorders
Yingying Cong, Vincent So, Marina A. J. Tijssen, Dineke S. Verbeek, Fulvio Reggiori, Mario Mauthe
Autophagy.2021; 17(12): 3908. CrossRef

Patients and Their Caregivers’ Burdens for Parkinson’s Disease in Korea: Jong Sam Baik, Joong-Seok Kim, Seong-Beom Koh, Jin Whan Cho, Phil Hyu Lee, Hyeo-Il Ma, Yun Joong Kim, Tae-Beom Ahn, Sang Jin Kim, Yong Duk Kim, Seong-min Choi, Ho-Won Lee, Hee Tae Kim; J Mov Disord. 2017;10(3):109-115. Published online September 22, 2017; DOI: https://doi.org/10.14802/jmd.17053

8,063 View
234 Download
12 Web of Science
11 Crossref

Abstract PDF

Objective
Many patients with Parkinson’s disease (PD) suffer from motor and non-motor symptoms. According to these variable symptoms of PD, patients or caregivers have a poorer quality of life than patients with other neurodegenerative diseases. Since the difficulties are varied for all patients, prioritizing their difficulties differs among all cases. The goal of this study was to investigate the burdens of PD among the caregivers as well as patients and to identify areas requiring aid from the government.
Methods
We surveyed the awareness and perceptions of PD in patients and caregivers of PD by a face-to-face questionnaire. The questionnaire was divided into three sections: symptoms of PD (part A), desire for policies (part B), and difficulties faced by their caregivers (part C). Part A comprised 8 questions, Part B had 2 questions, and Part C had 3 questions.
Results
In total, 853 subjects (702 patients and 151 caregivers) were enrolled in this study. The major difficulties experienced by PD patients were physical (67%), psychiatric (60%) and socio-economic (52%). Assessing the physical difficulties, more than half the patients experienced severe difficulties (29% very severe, 39% severe). Psychiatric difficulties were assessed as severe (35%) and very severe (21%) among the patients. Severe difficulties were also experienced socio-economically, at 52% in patients and 49% in caregivers, especially among patients in their fifties (58%) and those with their spouse (65%) as caregivers. The topmost need was the introduction of new technology for treatment of PD (62%), followed by relief of costs for treatment (38%) and a family support system (31%). The majority (91%) of the patients were diagnosed with PD within two years after onset of symptoms.
Conclusion
We know that the difficulties of PD and the needs for government assistance are different between patients and caregivers. These results emphasize that perceiving the difficulties and needs of patients and caregivers early can help to prevent and ameliorate the burden of disease.

Citations

Citations to this article as recorded by

Challenges in Parkinson’s Disease Care—In Light of the COVID-19 Pandemic
Kyung Ah Woo, Han-Joon Kim, Beomseok Jeon
Journal of Movement Disorders.2023; 16(1): 52. CrossRef
Efficacy and safety of a combination of emotional freedom technique with acupuncture versus acupuncture alone to treat psychiatric symptoms in Parkinson’s disease: A protocol for a randomized, assessor-blind, parallel-group clinical trial
Dong-Hoon Kang, Ju-Yeon Kim, Yang-Chun Park, Ho-Ryong Yoo, In Chul Jung
Medicine.2023; 102(21): e33714. CrossRef
Exploring Unmet Information Needs of People with Parkinson’s Disease and Their Families: Focusing on Information Sharing in an Online Patient Community
Hyeon Sik Chu, Hye Young Jang
International Journal of Environmental Research and Public Health.2022; 19(5): 2521. CrossRef
Participants' perspective on a COVID-19 online vocal group stimulation for people with Parkinson's disease
Marie-Christine Hallé, Charline Delorme, Édith Coulombe, Ouswa Rekik, Ingrid Verduyckt
Frontiers in Rehabilitation Sciences.2022;[Epub] CrossRef
Group singing improves quality of life for people with Parkinson’s: an international study
J. Yoon Irons, Grenville Hancox, Trish Vella-Burrows, Eun-Young Han, Hyun-Ju Chong, David Sheffield, Donald E. Stewart
Aging & Mental Health.2021; 25(4): 650. CrossRef
Exploring the perceptions and stigmatizing experiences of Israeli family caregivers of people with Parkinson's disease
Hanan AboJabel, Einat Argavan, Sharon Hassin-Baer, Rivka Inzelberg, Perla Werner
Journal of Aging Studies.2021; 56: 100910. CrossRef
Perceived online social support for Parkinson’s disease patients: The role of support type, uncertainty, contentment, and psychological quality of life
Surin Chung, Eunjin (Anna) Kim, J. Brian Houston
Communication Quarterly.2021; 69(3): 259. CrossRef
Delivering patient-centered care in Parkinson's disease: Challenges and consensus from an international panel
Roongroj Bhidayasiri, Pattamon Panyakaew, Claudia Trenkwalder, Beomseok Jeon, Nobutaka Hattori, Priya Jagota, Yih-Ru Wu, Elena Moro, Shen-Yang Lim, Huifang Shang, Raymond Rosales, Jee-Young Lee, Win Min Thit, Eng-King Tan, Thien Thien Lim, Ngoc Tai Tran,
Parkinsonism & Related Disorders.2020; 72: 82. CrossRef
Understanding patients’ and caregivers’ perspectives and educational needs in Parkinson’s disease: a multi-ethnic Asian study
Xing Yan Choo, Shen-Yang Lim, Karuthan Chinna, Yan Jing Tan, Voon Wei Yong, Jia Lun Lim, Kar Foo Lau, Jing Yi Chung, Jun Min Em, Hui Ting Tan, Jia Hwa Lim, Seng Beng Tan, Chong Tin Tan, Ai Huey Tan
Neurological Sciences.2020; 41(10): 2831. CrossRef
Nörolojik Hastalık ve Evlilik
Mehmet ÖNGER, Tuba AYDIN
Sakarya Medical Journal.2020;[Epub] CrossRef
The burden of care and the understanding of disease in Parkinson’s disease
Geum-Bong Lee, Hyunhee Woo, Su-Yoon Lee, Sang-Myung Cheon, Jae Woo Kim, Oscar Arias-Carrion
PLOS ONE.2019; 14(5): e0217581. CrossRef

Validation of the Korean Version of the Scale for Outcomes in Parkinson’s Disease-Autonomic: Ji-Young Kim, In-Uk Song, Seong-Beom Koh, Tae-Beom Ahn, Sang Jin Kim, Sang-Myung Cheon, Jin Whan Cho, Yun Joong Kim, Hyeo-Il Ma, Mee-Young Park, Jong Sam Baik, Phil Hyu Lee, Sun Ju Chung, Jong-Min Kim, Han-Joon Kim, Young-Hee Sung, Do Young Kwon, Jae-Hyeok Lee, Jee-Young Lee, Ji Sun Kim, Ji Young Yun, Hee Jin Kim, Jin Young Hong, Mi-Jung Kim, Jinyoung Youn, Ji Seon Kim, Eung Seok Oh, Hui-Jun Yang, Won Tae Yoon, Sooyeoun You, Kyum-Yil Kwon, Hyung-Eun Park, Su-Yun Lee, Younsoo Kim, Hee-Tae Kim, Joong-Seok Kim; J Mov Disord. 2017;10(1):29-34. Published online January 18, 2017; DOI: https://doi.org/10.14802/jmd.16057

16,770 View
380 Download
37 Web of Science
37 Crossref

Abstract PDF Supplementary Material

Objective
Autonomic symptoms are commonly observed in patients with Parkinson’s disease (PD) and often limit the activities of daily living. The Scale for Outcomes in Parkinson’s disease-Autonomic (SCOPA-AUT) was developed to evaluate and quantify autonomic symptoms in PD. The goal of this study was to translate the original SCOPA-AUT, which was written in English, into Korean and to evaluate its reliability and validity for Korean PD patients.
Methods
For the translation, the following processes were performed: forward translation, backward translation, expert review, pretest of the pre-final version and development of the final Korean version of SCOPA-AUT (K-SCOPA-AUT). In total, 127 patients with PD from 31 movement disorder clinics of university-affiliated hospitals in Korea were enrolled in this study. All patients were assessed using the K-SCOPA-AUT and other motor, non-motor, and quality of life scores. Test-retest reliability for the K-SCOPA-AUT was assessed over a time interval of 10−14 days.
Results
The internal consistency and reliability of the K-SCOPA-AUT was 0.727 as measured by the mean Cronbach’s α-coefficient. The test-retest correlation reliability was 0.859 by the Guttman split-half coefficient. The total K-SCOPA-AUT score showed a positive correlation with other non-motor symptoms [the Korean version of non-motor symptom scale (K-NMSS)], activities of daily living (Unified Parkinson’s Disease Rating Scale part II) and quality of life [the Korean version of Parkinson’s Disease Quality of Life 39 (K-PDQ39)].
Conclusion
The K-SCOPA-AUT had good reliability and validity for the assessment of autonomic dysfunction in Korean PD patients. Autonomic symptom severities were associated with many other motor and non-motor impairments and influenced quality of life.

Citations

Citations to this article as recorded by

Mild behavioral impairment in idiopathic REM sleep behavior disorder and Lewy body disease continuum
Bora Jin, Eun Jin Yoon, Kyung Ah Woo, Seoyeon Kim, Seungmin Lee, Ryul Kim, Jung Hwan Shin, Yu Kyeong Kim, Jee-Young Lee
Journal of Neural Transmission.2025;[Epub] CrossRef
Clinical characteristics and phenoconversion in isolated REM sleep behavior disorder: a prospective single-center study in Korea, compared with Montreal cohort
Jung-Ick Byun, Jun-Sang Sunwoo, Yong Woo Shin, Jung-Won Shin, Tae-Joon Kim, Jin-Sun Jun, Jung Hwan Shin, Han-Joon Kim, Jacques Montplaisir, Jean-François Gagnon, Amelie Pelletier, Aline Delva, Ronald B. Postuma, Ki-Young Jung
Journal of Clinical Sleep Medicine.2025; 21(1): 81. CrossRef
Impact of motor features on non‐motor symptoms in patients with de novo Parkinson's disease: Cognition, depression, anxiety, fatigue, and dysautonomia
Kyum‐Yil Kwon, Byung‐Euk Joo, Jihwan You, Rae On Kim
Geriatrics & Gerontology International.2025;[Epub] CrossRef
The Korean medicine for aging cohort (KoMAC) study: A protocol for a prospective, multicenter cohort study on healthy aging in the population entering old age in South Korea
Mi Mi Ko, Seojae Jeon, Wonbae Ha, Young-Eun Kim, So Young Jung, Bo-Young Kim, Myunghwa Kim, Kwang-Ho Choi, Geonhui Kang, So Min Lee, You Mee Ahn, Nahyun Cho, Hanbit Jin, Jungtae Leem, Seungkwan Choi, Jungho Jo, Junghan Lee, Jeeyoun Jung, Tatsuo Shimosawa
PLOS ONE.2025; 20(2): e0316986. CrossRef
Baseline prevalence and longitudinal assessment of autonomic dysfunction in early Parkinson’s disease
Lanqing Yang, Huan Gao, Min Ye
Journal of Neural Transmission.2024; 131(2): 127. CrossRef
Clinical Characteristics and Relevance of Dizziness in Patients with de novo Parkinson’s Disease
Kyum-Yil Kwon, Jihwan You, Rae On Kim, Eun Ji Lee
Journal of Integrative Neuroscience.2024;[Epub] CrossRef
Association Between Gait and Dysautonomia in Patients With De Novo Parkinson’s Disease: Forward Gait Versus Backward Gait
Seon-Min Lee, Mina Lee, Eun Ji Lee, Rae On Kim, Yongduk Kim, Kyum-Yil Kwon
Journal of Movement Disorders.2023; 16(1): 59. CrossRef
Beyond shallow feelings of complex affect: Non-motor correlates of subjective emotional experience in Parkinson’s disease
Claudia Carricarte Naranjo, Claudia Sánchez Luaces, Ivonne Pedroso Ibáñez, Andrés Machado, Hichem Sahli, María Antonieta Bobes, Vincenzo De Luca
PLOS ONE.2023; 18(2): e0281959. CrossRef
Autonomic function and motor subtypes in Parkinson’s disease: a multicentre cross-sectional study
Si-Chun Gu, Rong Shi, Chen Gao, Xiao-Lei Yuan, You Wu, Zhen-Guo Liu, Chang-De Wang, Shao-Rong Zhao, Xiqun Chen, Can-Xing Yuan, Qing Ye
Scientific Reports.2023;[Epub] CrossRef
Association of Dizziness-Related Handicap or Disability with Clinical Features in Patients with Early Parkinson’s Disease
Kyum-Yil Kwon, Jihwan You, Rae On Kim, Eun Ji Lee
Journal of Integrative Neuroscience.2023;[Epub] CrossRef
Clinical manifestation of patients with isolated rapid eye movement sleep behavior disorder after modest-to-long disease duration
Jung Kyung Hong, Jong-Min Kim, Ki-woong Kim, Ji Won Han, Soyeon Ahn, In-Young Yoon
Sleep.2022;[Epub] CrossRef
Associations of cognitive dysfunction with motor and non-motor symptoms in patients with de novo Parkinson’s disease
Kyum-Yil Kwon, Suyeon Park, Rae On Kim, Eun Ji Lee, Mina Lee
Scientific Reports.2022;[Epub] CrossRef
Autonomic dysfunction in Parkinson's disease: Results from the Faroese Parkinson's disease cohort
Aksel Berg, Sára Bech, Jan Aasly, Matthew J. Farrer, Maria Skaalum Petersen
Neuroscience Letters.2022; 785: 136789. CrossRef
Prevalence of lower urinary tract symptoms, urinary incontinence and retention in Parkinson's disease: A systematic review and meta-analysis
Fang-Fei Li, Yu-Sha Cui, Rui Yan, Shuang-Shuang Cao, Tao Feng
Frontiers in Aging Neuroscience.2022;[Epub] CrossRef
White matter tract-specific microstructural disruption is associated with depressive symptoms in isolated RBD
Jung-Ick Byun, Seunghwan Oh, Jun-Sang Sunwoo, Jung-Won Shin, Tae-Joon Kim, Jin-Sun Jun, Han-Joon Kim, Won Chul Shin, Joon-Kyung Seong, Ki-Young Jung
NeuroImage: Clinical.2022; 36: 103186. CrossRef
Comparison of disease progression between brain-predominant Parkinson's disease versus Parkinson's disease with body-involvement phenotypes
Dong-Woo Ryu, Sang-Won Yoo, Yoon-Sang Oh, Kwang-Soo Lee, Seunggyun Ha, Joong-Seok Kim
Neurobiology of Disease.2022; 174: 105883. CrossRef
Corneal confocal microscopy differentiates patients with Parkinson’s disease with and without autonomic involvement
Ning-Ning Che, Shuai Chen, Qiu-Huan Jiang, Si-Yuan Chen, Zhen-Xiang Zhao, Xue Li, Rayaz A. Malik, Jian-Jun Ma, Hong-Qi Yang
npj Parkinson's Disease.2022;[Epub] CrossRef
Association of Nucleus Basalis of Meynert Functional Connectivity and Cognition in Idiopathic Rapid-Eye-Movement Sleep Behavior Disorder
Jung-Ick Byun, Kwang Su Cha, Minah Kim, Woo-Jin Lee, Han Sang Lee, Jun-Sang Sunwoo, Jung-Won Shin, Tae-Joon Kim, Jin-Sun Jun, Han-Joon Kim, Won Chul Shin, Carlos H. Schenck, Sang Kun Lee, Ki-Young Jung
Journal of Clinical Neurology.2022; 18(5): 562. CrossRef
White Matter Tract-Specific Microstructural Disruption is Associated with Depressive Symptoms in Isolated Rbd
Jung-Ick Byun, Seunghwan Oh, Jun-Sang Sunwoo, Jung-Won Shin, Tae-Joon Kim, Jin-Sun Jun, Han-Joon Kim, Won Chul Shin, Joon-Kyung Seong, Ki-Young Jung
SSRN Electronic Journal .2022;[Epub] CrossRef
Impact of subjective dizziness on motor and non-motor symptoms in patients with early stages of Parkinson's disease
Kyum-Yil Kwon, Suyeon Park, Eun Ji Lee, Mina Lee, Hyunjin Ju
Journal of Integrative Neuroscience.2022;[Epub] CrossRef
Altered insular functional connectivity in isolated REM sleep behavior disorder: a data-driven functional MRI study
Jung-Ick Byun, Kwang Su Cha, Minah Kim, Woo-Jin Lee, Han Sang Lee, Jun-Sang Sunwoo, Jung-Won Shin, Tae-Joon Kim, Jangsup Moon, Soon-Tae Lee, Keun-Hwa Jung, Kon Chu, Man-Ho Kim, Han-Joon Kim, Won Chul Shin, Sang Kun Lee, Ki-Young Jung
Sleep Medicine.2021; 79: 88. CrossRef
Association of fall risk factors and non-motor symptoms in patients with early Parkinson’s disease
Kyum-Yil Kwon, Suyeon Park, Eun Ji Lee, Mina Lee, Hyunjin Ju
Scientific Reports.2021;[Epub] CrossRef
Impact of motor subtype on non‐motor symptoms and fall‐related features in patients with early Parkinson's disease
Kyum‐Yil Kwon, Eun Ji Lee, Mina Lee, Hyunjin Ju, Kayeong Im
Geriatrics & Gerontology International.2021; 21(5): 416. CrossRef
Extra-basal ganglia iron content and non-motor symptoms in drug-naïve, early Parkinson’s disease
Minkyeong Kim, Seulki Yoo, Doyeon Kim, Jin Whan Cho, Ji Sun Kim, Jong Hyun Ahn, Jun Kyu Mun, Inyoung Choi, Seung-Kyun Lee, Jinyoung Youn
Neurological Sciences.2021; 42(12): 5297. CrossRef
Clinical Assessment Scales in Autonomic Nervous System Disorders
Eun Bin Cho, Ki-Jong Park
Journal of the Korean Neurological Association.2021; 39(2 Suppl): 60. CrossRef
Cardiac sympathetic burden reflects Parkinson disease burden, regardless of high or low orthostatic blood pressure changes
Sang-Won Yoo, Joong-Seok Kim, Yoon-Sang Oh, Dong-Woo Ryu, Seunggyun Ha, Ji-Yeon Yoo, Kwang-Soo Lee
npj Parkinson's Disease.2021;[Epub] CrossRef
Understanding fatigue in progressive supranuclear palsy
Jong Hyeon Ahn, Joomee Song, Dong Yeong Lee, Jinyoung Youn, Jin Whan Cho
Scientific Reports.2021;[Epub] CrossRef
Validation of the Korean version of the composite autonomic symptom scale 31 in patients with Parkinson’s disease
Jong Hyeon Ahn, Jin Myoung Seok, Jongkyu Park, Heejeong Jeong, Younsoo Kim, Joomee Song, Inyoung Choi, Jin Whan Cho, Ju-Hong Min, Byoung Joon Kim, Jinyoung Youn, Antonina Luca
PLOS ONE.2021; 16(10): e0258897. CrossRef
Cardiac Autonomic Dysfunction Is Associated with Severity of REM Sleep without Atonia in Isolated REM Sleep Behavior Disorder
Sooyeoun You, Kyoung Sook Won, Keun Tae Kim, Hyang Woon Lee, Yong Won Cho
Journal of Clinical Medicine.2021; 10(22): 5414. CrossRef
Characteristics of Autonomic Dysfunction in Parkinson’s Disease: A Large Chinese Multicenter Cohort Study
Zhou Zhou, Xiaoting Zhou, Xiaoxia Zhou, Yaqin Xiang, Liping Zhu, Lixia Qin, Yige Wang, Hongxu Pan, Yuwen Zhao, Qiying Sun, Qian Xu, Xinyin Wu, Xinxiang Yan, Jifeng Guo, Beisha Tang, Zhenhua Liu
Frontiers in Aging Neuroscience.2021;[Epub] CrossRef
Autonomic Dysfunction in Parkinson's Disease: Results from the Faroese Parkinson's Disease Cohort
Aksel Kambsskarð Berg, Sára Bech, Jan O. Aasly, Matthew J. Farrer, Maria Skaalum Petersen
SSRN Electronic Journal .2021;[Epub] CrossRef
Subtypes of Sleep Disturbance in Parkinson's Disease Based on the Cross-Culturally Validated Korean Version of Parkinson's Disease Sleep Scale-2
Hui-Jun Yang, Han-Joon Kim, Seong-Beom Koh, Joong-Seok Kim, Tae-Beom Ahn, Sang-Myung Cheon, Jin Whan Cho, Yoon-Joong Kim, Hyeo-Il Ma, Mee Young Park, Jong Sam Baik, Phil Hyu Lee, Sun Ju Chung, Jong-Min Kim, In-Uk Song, Ji-Young Kim, Young-Hee Sung, Do You
Journal of Clinical Neurology.2020; 16(1): 66. CrossRef
Risk Factors for Falls in Patients with de novo Parkinson’s Disease: A Focus on Motor and Non-Motor Symptoms
Kyum-Yil Kwon, Mina Lee, Hyunjin Ju, Kayeong Im
Journal of Movement Disorders.2020; 13(2): 142. CrossRef
Peripheral Blood Inflammatory Cytokines in Idiopathic REM Sleep Behavior Disorder
Ryul Kim, Jin‐Sun Jun, Han‐Joon Kim, Ki‐Young Jung, Yong‐Won Shin, Tae‐Won Yang, Keun Tae Kim, Tae‐Joon Kim, Jung‐Ick Byun, Jun‐Sang Sunwoo, Beomseok Jeon
Movement Disorders.2019; 34(11): 1739. CrossRef
Urinary Dysfunctions and Post-Void Residual Urine in Typical and Atypical Parkinson Diseases
Yang-Hyun Lee, Jee-Eun Lee, Dong-Woo Ryu, Yoon-Sang Oh, Kwang-Soo Lee, Sung-Hoo Hong, Joong-Seok Kim
Journal of Parkinson’s Disease.2018; 8(1): 145. CrossRef
Rasch Analysis of the Clinimetric Properties of the Korean Dizziness Handicap Inventory in Patients with Parkinson Disease
Da-Young Lee, Hui-Jun Yang, Dong-Seok Yang, Jin-Hyuk Choi, Byoung-Soo Park, Ji-Yun Park
Research in Vestibular Science.2018; 17(4): 152. CrossRef
Clinical Characteristics of Parkinson’s Disease Developed from Essential Tremor
Dong-Woo Ryu, Si-Hoon Lee, Yoon-Sang Oh, Jae-Young An, Jeong-Wook Park, In-Uk Song, Kwang-Soo Lee, Joong-Seok Kim
Journal of Parkinson’s Disease.2017; 7(2): 369. CrossRef

Metronidazole-Induced Craniocervical Myoclonus with Reversible Bilateral Dentate Nucleus Lesions: Hyun Chang Lee, Young Eun Kim, Hyeo-Il Ma; J Mov Disord. 2017;10(1):67-68. Published online January 18, 2017; DOI: https://doi.org/10.14802/jmd.16021

13,201 View
121 Download
2 Web of Science
2 Crossref

PDF

Citations

Citations to this article as recorded by

Metronidazole-induced encephalopathy: a systematic review
Caspar Godthaab Sørensen, William Kristian Karlsson, Faisal Mohammad Amin, Mette Lindelof
Journal of Neurology.2020; 267(1): 1. CrossRef
Persistent dystonia and basal ganglia involvement following metronidazole induced encephalopathy
Abdolmajid Omrani, Mohammad Rohani, Sareh Hosseinpour, Ali Reza Tavasoli
Neurological Sciences.2020; 41(4): 957. CrossRef

N30 Somatosensory Evoked Potential Is Negatively Correlated with Motor Function in Parkinson’s Disease: Suk Yun Kang, Hyeo-Il Ma; J Mov Disord. 2016;9(1):35-39. Published online January 25, 2016; DOI: https://doi.org/10.14802/jmd.15038

26,276 View
91 Download
7 Web of Science
5 Crossref

Abstract PDF

Objective
aaThe aim of this study was to investigate frontal N30 status in Parkinson’s disease (PD) and to examine the correlation between the amplitude of frontal N30 and the severity of motor deficits.
Methods
aaThe frontal N30 was compared between 17 PD patients and 18 healthy volunteers. Correlations between the amplitude of frontal N30 and the Unified Parkinson’s Disease Rating Scale (UPDRS) motor score of the more severely affected side was examined.
Results
aaThe mean latency of the N30 was not significantly different between patients and healthy volunteers (p = 0.981), but the mean amplitude was lower in PD patients (p < 0.025). There was a significant negative correlation between the amplitude of N30 and the UPDRS motor score (r = -0.715, p = 0.013).
Conclusions
The frontal N30 status indicates the motor severity of PD. It can be a useful biomarker reflecting dopaminergic deficits and an objective measurement for monitoring the clinical severity of PD.

Citations

Citations to this article as recorded by

A Comparison of Sensorimotor Integration and Motor Fitness Components between Collegiate Athletes with and without Long COVID: A Cross-Sectional Study with Pair-Matched Controls
Ibrahim M. Moustafa, Amal Ahbouch, Raheesa P. Kader, Tamer Mohamed Shousha, Abdulla Alrahoomi
Journal of Clinical Medicine.2024; 13(9): 2469. CrossRef
The Effects of Chiropractic Spinal Adjustment on EEG in Adults with Alzheimer's and Parkinson's Disease: A Pilot Randomised Cross-over Trial
Muhammad Samran Navid, Imran Khan Niazi, Kelly Holt, Rasmus Bach Nedergaard, Imran Amjad, Usman Ghani, Nitika Kumari, Muhammad Shafique, Jenna Duehr, Robert J. Trager, Heidi Haavik
Journal of Integrative Neuroscience.2024;[Epub] CrossRef
Spatial discrimination in patients with MSA, PSP, DIP, and VP with pain
Min Seung Kim, Jaeho Kim, Suk Yun Kang
Scientific Reports.2024;[Epub] CrossRef
Clinical factors affecting evoked magnetic fields in patients with Parkinson's disease
Ryoji Naganuma, Ichiro Yabe, Megumi Takeuchi, Kirari Morishita, Shingo Nakane, Ryoken Takase, Ikuko Takahashi-Iwata, Masaaki Matsushima, Mika Otsuki, Hideaki Shiraishi, Hidenao Sasaki, Wing-ho Yung
PLOS ONE.2020; 15(9): e0232808. CrossRef
Short-Term Effects of Thoracic Spine Manipulation on the Biomechanical Organisation of Gait Initiation: A Randomized Pilot Study
Sébastien Ditcharles, Eric Yiou, Arnaud Delafontaine, Alain Hamaoui
Frontiers in Human Neuroscience.2017;[Epub] CrossRef

Current Status of Huntington’s Disease in Korea: A Nationwide Survey and National Registry Analysis: Hyun Sook Kim, Chul Hyoung Lyoo, Phil Hyu Lee, Sang Jin Kim, Mee Young Park, Hyeo-Il Ma, Jae Hyeok Lee, Sook Kun Song, Jong Sam Baik, Jin Ho Kim, Myung Sik Lee; J Mov Disord. 2015;8(1):14-20. Published online January 31, 2015; DOI: https://doi.org/10.14802/jmd.14038

19,744 View
131 Download
23 Web of Science
21 Crossref

Abstract PDF

Objective Huntington’s disease (HD) is a rare neurological disorder, and its current status in Korea is not well investigated. This study aims to determine the prevalence and incidence of HD and to investigate the clinical features of HD patients in Korea.
Methods We estimated the crude prevalence and annual incidence of HD based on the databases of the Rare Diseases Registry (RDR) and the National Health Insurance (NHI). The clinical data of genetically confirmed HD patients was collected from 10 referral hospitals and analyzed.
Results The mean calculated annual incidence was 0.06 cases per 100,000 persons, and the mean calculated prevalence was 0.38 based on the NHI database. The estimated crude prevalence based on the RDR was 0.41. Of the sixty-eight HD patients recruited, the mean age of onset was 44.16 ± 14.08 years and chorea was most frequently reported as the initial symptom and chief complaint. The mean CAG repeat number of the expanded allele was 44.7 ± 4.8 and correlated inversely with the age of onset (p < 0.001). About two-thirds of the patients have a positive family history, and HD patients without positive family history showed a delay in onset of initial symptoms, a prolonged interval between initial symptom onset and genetic diagnosis and a delay in the age of genetic diagnosis.
Conclusions To the best of our knowledge, this is the first study to estimate the prevalence and incidence of HD in Korea and the largest HD series in the Asian population. Our analyses might be useful for further studies and large-scale investigations in HD patients.

Citations

Citations to this article as recorded by

Analysis of HTT CAG repeat expansion among healthy individuals and patients with chorea in Korea
Ryul Kim, Moon-Woo Seong, Bumjo Oh, Ho Seop Shin, Jee-Soo Lee, Sangmin Park, Mihee Jang, Beomseok Jeon, Han-Joon Kim, Jee-Young Lee
Parkinsonism & Related Disorders.2024; 118: 105930. CrossRef
Neurodegenerative disorders: Mechanisms of degeneration and therapeutic approaches with their clinical relevance
Dnyandev G. Gadhave, Vrashabh V. Sugandhi, Saurav Kumar Jha, Sopan N. Nangare, Gaurav Gupta, Sachin Kumar Singh, Kamal Dua, Hyunah Cho, Philip M. Hansbro, Keshav Raj Paudel
Ageing Research Reviews.2024; 99: 102357. CrossRef
Clinical and Genetic Characteristics Associated With Survival Outcome in Late-Onset Huntington’s Disease in South Korea
Yun Su Hwang, Sungyang Jo, Gu-Hwan Kim, Jee-Young Lee, Ho-Sung Ryu, Eungseok Oh, Seung-Hwan Lee, Young Seo Kim, Sun Ju Chung
Journal of Clinical Neurology.2024; 20(4): 394. CrossRef
Epidemiology of Chronic Inflammatory Demyelinating Polyneuropathy in South Korea: A Population-Based Study
Sohee Jung, Gucheol Jung, Dayoung Kim, Jeeyoung Oh, Kyomin Choi
Journal of Clinical Neurology.2023; 19(6): 558. CrossRef
Increased 10-Year Prevalence of Huntington’s Disease in South Korea: An Analysis of Medical Expenditure Through the National Healthcare System
Chan Young Lee, Jun-soo Ro, Hyemin Jung, Manho Kim, Beomseok Jeon, Jee-Young Lee
Journal of Clinical Neurology.2023; 19(2): 147. CrossRef
Global Epidemiology of Movement Disorders: Rare or Underdiagnosed?
Sarah A. O'Shea, Ludy C. Shih
Seminars in Neurology.2023; 43(01): 004. CrossRef
Huntington’s Disease in Chile: Epidemiological and Genetic Aspects
Ernesto Solís-Añez, Philippe A. Salles, Natalia Rojas, Olga Benavides, Pedro Chaná-Cuevas
Neuroepidemiology.2023; 57(3): 176. CrossRef
Epidemiology of Acute Leukemia among Children with Down Syndrome in Korea
Young Bae Choi, Keon Hee Yoo
Cancer Research and Treatment.2022; 54(2): 572. CrossRef
Population Prevalence, Cancer Risk, and Mortality Risk of Turner Syndrome in South Korean Women Based on National Health Insurance Service Data
Sung Eun Kim, Sang Hyun Park, Kyungdo Han, Won Kyoung Cho, Byung-Kyu Suh, Yong-Gyu Park
Yonsei Medical Journal.2022; 63(11): 991. CrossRef
Prevalence and Incidence of Huntington's Disease: An Updated Systematic Review and Meta‐Analysis
Alex Medina, Yasamin Mahjoub, Larry Shaver, Tamara Pringsheim
Movement Disorders.2022; 37(12): 2327. CrossRef
Contemporary Status of Acute Myocardial Infarction in Korean Patients: Korean Registry of Acute Myocardial Infarction for Regional Cardiocerebrovascular Centers
Rock Bum Kim, Jin Yong Hwang, Hyun Woong Park, Ae-Young Her, Jang Hoon Lee, Moo Hyun Kim, Chang Hwan Yoon, Jae Young Cho, Sung-Il Woo, Yongcheol Kim, Jae-Young Han, Joon Hyouk Choi, Song Yi Kim, Si Wan Choi, Sung Ju Jee, Sang Yeub Lee, Ki-Bum Won, Kyeong-
Journal of Clinical Medicine.2021; 10(3): 498. CrossRef
Huntington’s Disease in Israel: A Population-Based Study Using 20 Years of Routinely-Collected Healthcare Data
Natalie Gavrielov-Yusim, Yael Barer, Michael Martinec, Athanasios Siadimas, Spyros Roumpanis, Hannah Furby, Inbal Goldshtein, Asif Jan, Preciosa M. Coloma
Journal of Huntington's Disease.2021; 10(4): 469. CrossRef
The Population Prevalence, Associations of Congenital Heart Defect and Mortality Risk for Down’s Syndrome in South Korea Based on National Health Insurance Service (NHIS) Data

Won Kyoung Cho, Na Young Lee, Kyungdo Han, Byung-Kyu Suh, Yong-Gyu Park
Clinical Epidemiology.2020; Volume 12: 519. CrossRef
Incidence of Huntington disease in a northeastern Spanish region: a 13-year retrospective study at tertiary care centre
Paula Sienes Bailo, Raquel Lahoz, Juan Pelegrín Sánchez Marín, Silvia Izquierdo Álvarez
BMC Medical Genetics.2020;[Epub] CrossRef
The molecular epidemiology of Huntington disease is related to intermediate allele frequency and haplotype in the general population
Chris Kay, Jennifer A. Collins, Galen E.B. Wright, Fiona Baine, Zosia Miedzybrodzka, Folefac Aminkeng, Alicia J. Semaka, Cassandra McDonald, Mark Davidson, Steven J. Madore, Erynn S. Gordon, Norman P. Gerry, Mario Cornejo‐Olivas, Ferdinando Squitieri, Sar
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.2018; 177(3): 346. CrossRef
Quantitative Gait Analysis in Patients with Huntington’s Disease
Seon Jong Pyo, Hanjun Kim, Il Soo Kim, Young-Min Park, Mi-Jung Kim, Hye Mi Lee, Seong-Beom Koh
Journal of Movement Disorders.2017; 10(3): 140. CrossRef
Epidemiological Study of Huntington's Disease in the Province of Ferrara, Italy
Erika Carrassi, Maura Pugliatti, Vittorio Govoni, Mariachiara Sensi, Ilaria Casetta, Enrico Granieri
Neuroepidemiology.2017; 49(1-2): 18. CrossRef
The Epidemiology of Myasthenia Gravis in Korea
Hyung Seok Lee, Hye Sun Lee, Ha Young Shin, Young-Chul Choi, Seung Min Kim
Yonsei Medical Journal.2016; 57(2): 419. CrossRef
The Global Prevalence of Huntington’s Disease: A Systematic Review and Discussion
Sheharyar Sajjad Baig, Mark Strong, Oliver WJ Quarrell
Neurodegenerative Disease Management.2016; 6(4): 331. CrossRef
Clinical and genetic characteristics in patients with Huntington’s disease from China
Jing Yang, Ke Chen, Qianqian Wei, Yongping Chen, Bei Cao, Jean-Marc Burgunder, Hui-Fang Shang
Neurological Research.2016; 38(10): 916. CrossRef
Survival of Korean Huntington’s Disease Patients
Han-Joon Kim, Chae-Won Shin, Beomseok Jeon, Hyeyoung Park
Journal of Movement Disorders.2016; 9(3): 166. CrossRef

A Case of Painful Hemimasticatory Spasm with Masseter Muscle Hypertrophy Responsive to Botulinum Toxin: Jin-Hyuck Kim, Seok-Won Han, Yun Joong Kim, Jooyong Kim, Mi-Suh Oh, Hyeo-Il Ma, Byung-Chul Lee; J Mov Disord. 2009;2(2):95-97.; DOI: https://doi.org/10.14802/jmd.09026

54,423 View
92 Download
7 Crossref

Abstract PDF

Hemimasticatory spasm (HMS) is a rare disorder of the trigeminal nerve characterized by paroxysmal involuntary contractions of the unilateral jaw-closing muscles. HMS has been frequently described in association with facial hemiatrophy or localized scleroderma. A 42-year-old female presented with involuntary paroxysmal spasms of the left face, of 6 months duration. Her lower face on the left was markedly hypertrophied without skin lesions. An electrophysiological study indicated that the masseter reflexes and masseteric silent period were attenuated on the affected side. Surface electromyography demonstrated irregular bursts of motor unit potentials at high frequencies up to 200 Hz. Magnetic resonance imaging of the head showed marked hypertrophy of the left masseter muscle. Biopsy of the hypertrophied masseter muscle was normal. Repeated local injections of botulinum toxin noticeably reduced the size of the hypertrophied muscle as well as improved the patient’s symptoms.

Citations

Citations to this article as recorded by

Hemimasticatory spasm: a series of 17 cases and a comprehensive review of the literature
Kazuya Yoshida
Frontiers in Neurology.2024;[Epub] CrossRef
A New Management Strategy for Hemimasticatory Spasm
Zhongding Zhang, Datan Lu, Tingting Ying, Shiting Li, Hua Zhao
Journal of Neurological Surgery Part A: Central European Neurosurgery.2024;[Epub] CrossRef
Hemimasticatory spasm: possibilities of treatment with injections of botulinum neuroprotein type A (case report)
L. U. Valieva, A. S. Pankratov, O. R. Orlova
Neurology, Neuropsychiatry, Psychosomatics.2022; 14(3): 62. CrossRef
Bilateral Hemimasticatory spasm in a patient with hypereosinophilic syndrome
Kyung Ah Woo, Han-Joon Kim, Hyeyoung Park, Beomseok Jeon
Parkinsonism & Related Disorders.2021; 93: 55. CrossRef
Hemimasticatory spasm. Own experience of using botulinum neuroprotein type A
A. N. Korenko, A. V. Amelin, A. A. Timofeeva
The Scientific Notes of the Pavlov University.2021; 28(3): 47. CrossRef
Parry-Romberg Syndrome With Hemimasticatory Spasm: A Rare Combination
Guang-can Chen, Min-jie Chen, Wen-bin Wei, Yun-bo Hao
Journal of Craniofacial Surgery.2020; 31(2): e205. CrossRef
Hemi Masticatory Spasm: Series of 7 Cases and Review of Literature
Divya M. Radhakrishnan, Vinay Goyal, Garima Shukla, Mamta Bhushan Singh, M. Ramam
Movement Disorders Clinical Practice.2019; 6(4): 316. CrossRef

Author index