Journal of Movement Disorders

Volume 12(3); September 2019

Review Articles

Modeling α-Synuclein Propagation with Preformed Fibril Injections: Hyun Kyung Chung, Hoang-Anh Ho, Dayana Pérez-Acuña, Seung-Jae Lee; J Mov Disord. 2019;12(3):139-151. Published online September 30, 2019; DOI: https://doi.org/10.14802/jmd.19046; Correction in: J Mov Disord 2020;13(1):77

16,808 View
889 Download
59 Web of Science
55 Crossref

The aggregation of α-synuclein (α-syn) has been implicated in the pathogenesis of many neurodegenerative disorders, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). Postmortem analyses of α-syn pathology, especially that of PD, have suggested that aggregates progressively spread from a few discrete locations to wider brain regions. The neuron-to-neuron propagation of α-syn has been suggested to be the underlying mechanism by which aggregates spread throughout the brain. Many cellular and animal models has been created to study cell-to-cell propagation. Recently, it has been shown that a single injection of preformed fibrils (PFFs) made of recombinant α-syn proteins into various tissues and organs of many different animal species results in widespread α-syn pathology in the central nervous system (CNS). These PFF models have been extensively used to study the mechanism by which aggregates spread throughout the brain. Here, we review what we have learned from PFF models, describe the nature of PFFs and the neuropathological features, neurophysiological characteristics, and behavioral outcomes of the models.

Citations

Citations to this article as recorded by

Glial senescence enhances α-synuclein pathology owing to its insufficient clearance caused by autophagy dysfunction
Bin Hong, Yosuke Ohtake, Takahide Itokazu, Toshihide Yamashita
Cell Death Discovery.2024;[Epub] CrossRef
A Surface Imprinted Polymer EIS Sensor for Detecting Alpha-Synuclein, a Parkinson’s Disease Biomarker
Roslyn Simone Massey, Rishabh Ramesh Appadurai, Ravi Prakash
Micromachines.2024; 15(2): 273. CrossRef
Dysbiosis of the gut microbiota and its effect on α-synuclein and prion protein misfolding: consequences for neurodegeneration
Nasir Uddin Mahbub, Md Minarul Islam, Seong-Tshool Hong, Hea-Jong Chung
Frontiers in Cellular and Infection Microbiology.2024;[Epub] CrossRef
Neuropathogenesis-on-chips for neurodegenerative diseases
Sarnai Amartumur, Huong Nguyen, Thuy Huynh, Testaverde S. Kim, Ran-Sook Woo, Eungseok Oh, Kyeong Kyu Kim, Luke P. Lee, Chaejeong Heo
Nature Communications.2024;[Epub] CrossRef
Systemic inflammation activates coagulation and immune cell infiltration pathways in brains with propagating α-synuclein fibril aggregates
Anne-Line Strange Laursen, Mikkel Vestergaard Olesen, Jonas Folke, Tomasz Brudek, Luisa Harriet Knecht, Florence Sotty, Kate Lykke Lambertsen, Karina Fog, Louise Torp Dalgaard, Susana Aznar
Molecular and Cellular Neuroscience.2024; 129: 103931. CrossRef
Non-invasive Monitoring of α-Synuclein in Saliva for Parkinson’s Disease Using Organic Electrolyte-Gated FET Aptasensor
Roslyn S. Massey, Erin M. McConnell, Dennis Chan, Matthew R. Holahan, Maria C. DeRosa, Ravi Prakash
ACS Sensors.2023; 8(8): 3116. CrossRef
CSF-derived extracellular vesicles from patients with Parkinson’s disease induce symptoms and pathology
Shay Herman, Ruth Djaldetti, Brit Mollenhauer, Daniel Offen
Brain.2023; 146(1): 209. CrossRef
Overexpression-Induced α-Synuclein Brain Spreading
Rita Pinto-Costa, Eugenia Harbachova, Pietro La Vitola, Donato A. Di Monte
Neurotherapeutics.2023; 20(1): 83. CrossRef
The Role of α-Synuclein in the Regulation of Serotonin System: Physiological and Pathological Features
Lluis Miquel-Rio, Unai Sarriés-Serrano, Rubén Pavia-Collado, J Javier Meana, Analia Bortolozzi
Biomedicines.2023; 11(2): 541. CrossRef
α‐Synuclein decoy peptide protects mice against α‐synuclein‐induced memory loss
Qingyun Guo, Ichiro Kawahata, Wenbin Jia, Haoyang Wang, An Cheng, Yasushi Yabuki, Norifumi Shioda, Kohji Fukunaga
CNS Neuroscience & Therapeutics.2023; 29(6): 1547. CrossRef
Duodenal alpha‐Synuclein Pathology and Enteric Gliosis in Advanced Parkinson's Disease
Aron Emmi, Michele Sandre, Francesco Paolo Russo, Giulia Tombesi, Federica Garrì, Marta Campagnolo, Miryam Carecchio, Roberta Biundo, Gaya Spolverato, Veronica Macchi, Edoardo Savarino, Fabio Farinati, Piero Parchi, Andrea Porzionato, Luigi Bubacco, Raffa
Movement Disorders.2023; 38(5): 885. CrossRef
Retina-to-brain spreading of α-synuclein after intravitreal injection of preformed fibrils
Dayana Pérez-Acuña, Ka Hyun Rhee, Soo Jean Shin, Jeeyun Ahn, Jee-Young Lee, Seung-Jae Lee
Acta Neuropathologica Communications.2023;[Epub] CrossRef
Apathy in Parkinson’s Disease: Clinical Patterns and Neurobiological Basis
Matthieu Béreau, Vincent Van Waes, Mathieu Servant, Eloi Magnin, Laurent Tatu, Mathieu Anheim
Cells.2023; 12(12): 1599. CrossRef
Translating Pathological Brain Activity Primers in Parkinson’s Disease Research
Daniela Mirzac, Svenja L. Kreis, Heiko J. Luhmann, Gabriel Gonzalez-Escamilla, Sergiu Groppa
Research.2023;[Epub] CrossRef
Animal models of Parkinson’s disease: bridging the gap between disease hallmarks and research questions
Axelle Dovonou, Cyril Bolduc, Victoria Soto Linan, Charles Gora, Modesto R. Peralta III, Martin Lévesque
Translational Neurodegeneration.2023;[Epub] CrossRef
The Poly-Arginine Peptide R18D Interferes with the Internalisation of α-Synuclein Pre-Formed Fibrils in STC-1 Enteroendocrine Cells
Anastazja M. Gorecki, Holly Spencer, Bruno P. Meloni, Ryan S. Anderton
Biomedicines.2023; 11(8): 2089. CrossRef
Alpha‐synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain
Shuyu Zhang, Karina Dauer, Timo Strohäker, Lars Tatenhorst, Lucas Caldi Gomes, Simon Mayer, Byung Chul Jung, Woojin S. Kim, Seung‐Jae Lee, Stefan Becker, Friederike Liesche‐Starnecker, Markus Zweckstetter, Paul Lingor
Brain Pathology.2023;[Epub] CrossRef
Aging, Parkinson’s Disease, and Models: What Are the Challenges?
Emily Rocha, Manish Chamoli, Shankar J. Chinta, Julie K. Andersen, Ruby Wallis, Erwan Bezard, Matt Goldberg, Tim Greenamyre, Warren Hirst, We-Li Kuan, Deniz Kirik, Laura Niedernhofer, Irit Rappley, Shalini Padmanabhan, Louis-Eric Trudeau, Maria Spillantin
Aging Biology.2023; 1(1): 20230010. CrossRef
A Novel NOX Inhibitor Alleviates Parkinson’s Disease Pathology in PFF-Injected Mice
Kwadwo Ofori, Anurupa Ghosh, Dinesh Kumar Verma, Darice Wheeler, Gabriela Cabrera, Jong-Bok Seo, Yong-Hwan Kim
International Journal of Molecular Sciences.2023; 24(18): 14278. CrossRef
Cortical Lewy body injections induce long-distance pathogenic alterations in the non-human primate brain
Margaux Teil, Sandra Dovero, Mathieu Bourdenx, Marie-Laure Arotcarena, Morgane Darricau, Gregory Porras, Marie-Laure Thiolat, Inés Trigo-Damas, Celine Perier, Cristina Estrada, Nuria Garcia-Carrillo, María Trinidad Herrero, Miquel Vila, José A. Obeso, Erw
npj Parkinson's Disease.2023;[Epub] CrossRef
Immunization Effects of a Novel α-Synuclein-Based Peptide Epitope Vaccine in Parkinson’s Disease-Associated Pathology
Jun Sung Park, Riaz Ahmad, Kyonghwan Choe, Min Hwa Kang, Tae Ju Park, Myeong Ok Kim
Vaccines.2023; 11(12): 1820. CrossRef
Ellagic Acid Prevents α-Synuclein Spread and Mitigates Toxicity by Enhancing Autophagic Flux in an Animal Model of Parkinson’s Disease
Nada Radwan, Engila Khan, Mustafa T. Ardah, Tohru Kitada, M. Emdadul Haque
Nutrients.2023; 16(1): 85. CrossRef
DA-9805 protects dopaminergic neurons from endoplasmic reticulum stress and inflammation
Sora Kang, Ying Piao, Young Cheol Kang, Suyeol Lim, Youngmi Kim Pak
Biomedicine & Pharmacotherapy.2022; 145: 112389. CrossRef
Endogenous Levels of Alpha-Synuclein Modulate Seeding and Aggregation in Cultured Cells
Eftychia Vasili, Antonio Dominguez-Meijide, Manuel Flores-León, Mohammed Al-Azzani, Angeliki Kanellidi, Ronald Melki, Leonidas Stefanis, Tiago Fleming Outeiro
Molecular Neurobiology.2022; 59(2): 1273. CrossRef
Phosphorylation of endogenous α-synuclein induced by extracellular seeds initiates at the pre-synaptic region and spreads to the cell body
Shiori Awa, Genjiro Suzuki, Masami Masuda-Suzukake, Takashi Nonaka, Minoru Saito, Masato Hasegawa
Scientific Reports.2022;[Epub] CrossRef
Evidence of Inflammation in Parkinson’s Disease and Its Contribution to Synucleinopathy
Thuy Thi Lai, Yun Joong Kim, Hyeo-il Ma, Young Eun Kim
Journal of Movement Disorders.2022; 15(1): 1. CrossRef
α-Synuclein in Parkinson's disease and advances in detection
Rong Chen, Xuan Gu, Xiaoying Wang
Clinica Chimica Acta.2022; 529: 76. CrossRef
Neurons with Cat’s Eyes: A Synthetic Strain of α-Synuclein Fibrils Seeding Neuronal Intranuclear Inclusions
Francesca De Giorgi, Muhammed Bilal Abdul-Shukkoor, Marianna Kashyrina, Leslie-Ann Largitte, Francesco De Nuccio, Brice Kauffmann, Alons Lends, Florent Laferrière, Sébastien Bonhommeau, Dario Domenico Lofrumento, Luc Bousset, Erwan Bezard, Thierry Buffete
Biomolecules.2022; 12(3): 436. CrossRef
A Novel NOX Inhibitor Treatment Attenuates Parkinson’s Disease-Related Pathology in Mouse Models
Anurupa A. Ghosh, Dinesh Kumar Verma, Gabriela Cabrera, Kwadwo Ofori, Karina Hernandez-Quijada, Jae-Kwan Kim, Joo Hee Chung, Michael Moore, Sung Hwan Moon, Jong Bok Seo, Yong-Hwan Kim
International Journal of Molecular Sciences.2022; 23(8): 4262. CrossRef
Do Naturally Occurring Antioxidants Protect Against Neurodegeneration of the Dopaminergic System? A Systematic Revision in Animal Models of Parkinson's Disease
Carmen Costas, Lilian R.F. Faro
Current Neuropharmacology.2022; 20(2): 432. CrossRef
NXP031 prevents dopaminergic neuronal loss and oxidative damage in the AAV-WT-α-synuclein mouse model of Parkinson’s disease
Min Kyung Song, Levi Adams, Joo Hee Lee, Yoon-Seong Kim, Hemant K. Paudel
PLOS ONE.2022; 17(7): e0272085. CrossRef
Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo
Rachel E. Lackie, Aline S. de Miranda, Mei Peng Lim, Vladislav Novikov, Nimrod Madrer, Nadun C. Karunatilleke, Benjamin S. Rutledge, Stephanie Tullo, Anne Brickenden, Matthew E. R. Maitland, David Greenberg, Daniel Gallino, Wen Luo, Anoosha Attaran, Irina
Acta Neuropathologica.2022; 144(5): 881. CrossRef
Nanomedicine in the Face of Parkinson’s Disease: From Drug Delivery Systems to Nanozymes
Francisco J. Padilla-Godínez, Leonardo I. Ruiz-Ortega, Magdalena Guerra-Crespo
Cells.2022; 11(21): 3445. CrossRef
Animal Models of Metabolic Disorders in the Study of Neurodegenerative Diseases: An Overview
Andreza Fabro de Bem, Rachel Krolow, Hémelin Resende Farias, Victória Linden de Rezende, Daniel Pens Gelain, José Cláudio Fonseca Moreira, João Miguel das Neves Duarte, Jade de Oliveira
Frontiers in Neuroscience.2021;[Epub] CrossRef
Role of Liver Growth Factor (LGF) in Parkinson’s Disease: Molecular Insights and Therapeutic Opportunities
Efthalia Angelopoulou, Yam Nath Paudel, Christina Piperi
Molecular Neurobiology.2021; 58(7): 3031. CrossRef
Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain
Nelson Ferreira, Nádia Pereira Gonçalves, Asad Jan, Nanna Møller Jensen, Amelia van der Laan, Simin Mohseni, Christian Bjerggaard Vægter, Poul Henning Jensen
Acta Neuropathologica Communications.2021;[Epub] CrossRef
Pharmacological Inhibition of Brain EGFR Activation By a BBB-penetrating Inhibitor, AZD3759, Attenuates α-synuclein Pathology in a Mouse Model of α-Synuclein Propagation
Omid Tavassoly, Esther del Cid Pellitero, Frederique Larroquette, Eddie Cai, Rhalena A. Thomas, Vincent Soubannier, Wen Luo, Thomas M. Durcan, Edward A. Fon
Neurotherapeutics.2021; 18(2): 979. CrossRef
The Future of Incretin-Based Approaches for Neurodegenerative Diseases in Older Adults: Which to Choose? A Review of their Potential Efficacy and Suitability
Christine Girges, Nirosen Vijiaratnam, Dilan Athauda, Grace Auld, Sonia Gandhi, Thomas Foltynie
Drugs & Aging.2021; 38(5): 355. CrossRef
Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy
Nelson Ferreira, Mette Richner, Amelia van der Laan, Ida Bergholdt Jul Christiansen, Christian B Vægter, Jens R Nyengaard, Glenda M Halliday, Joachim Weis, Benoit I Giasson, Ian R Mackenzie, Poul H Jensen, Asad Jan
Brain Communications.2021;[Epub] CrossRef
Impact of the apelin/APJ axis in the pathogenesis of Parkinson’s disease with therapeutic potential
Efthalia Angelopoulou, Yam Nath Paudel, Anastasia Bougea, Christina Piperi
Journal of Neuroscience Research.2021; 99(9): 2117. CrossRef
Adenovirus-induced Reactive Astrogliosis Exacerbates the Pathology of Parkinson’s Disease
Heeyoung An, Hyowon Lee, Seulkee Yang, Woojin Won, C. Justin Lee, Min-Ho Nam
Experimental Neurobiology.2021; 30(3): 222. CrossRef
Brain iron enrichment attenuates α‐synuclein spreading after injection of preformed fibrils
Karina Dauer née Joppe, Lars Tatenhorst, Lucas Caldi Gomes, Shuyu Zhang, Mojan Parvaz, Eleonora Carboni, Anna‐Elisa Roser, Hazem El DeBakey, Mathias Bähr, Katarina Vogel‐Mikuš, Chi Wang Ip, Stefan Becker, Markus Zweckstetter, Paul Lingor
Journal of Neurochemistry.2021; 159(3): 554. CrossRef
Increased oscillatory power in a computational model of the olfactory bulb due to synaptic degeneration
J. Kendall Berry, Daniel Cox
Physical Review E.2021;[Epub] CrossRef
Combining Automated Organoid Workflows with Artificial Intelligence‐Based Analyses: Opportunities to Build a New Generation of Interdisciplinary High‐Throughput Screens for Parkinson's Disease and Beyond
Henrik Renner, Hans R. Schöler, Jan M. Bruder
Movement Disorders.2021; 36(12): 2745. CrossRef
Is Multiple System Atrophy a Prion-like Disorder?
Kurt A. Jellinger, Gregor K. Wenning, Nadia Stefanova
International Journal of Molecular Sciences.2021; 22(18): 10093. CrossRef
Cortical alpha-synuclein preformed fibrils do not affect interval timing in mice
Qiang Zhang, Hisham Abdelmotilib, Travis Larson, Cameron Keomanivong, Mackenzie Conlon, Georgina M. Aldridge, Nandakumar S. Narayanan
Neuroscience Letters.2021; 765: 136273. CrossRef
Temporal Evolution of Inflammation and Neurodegeneration With Alpha-Synuclein Propagation in Parkinson's Disease Mouse Model
Thuy Thi Lai, Yun Joong Kim, Phuong Thi Nguyen, Young Ho Koh, Tinh Thi Nguyen, Hyeo-il Ma, Young Eun Kim
Frontiers in Integrative Neuroscience.2021;[Epub] CrossRef
The Concept of α-Synuclein Strains and How Different Conformations May Explain Distinct Neurodegenerative Disorders
Katja Malfertheiner, Nadia Stefanova, Antonio Heras-Garvin
Frontiers in Neurology.2021;[Epub] CrossRef
A historical review of multiple system atrophy with a critical appraisal of cellular and animal models
David J. Marmion, Wouter Peelaerts, Jeffrey H. Kordower
Journal of Neural Transmission.2021; 128(10): 1507. CrossRef
Exploring the Etiological Links behind Neurodegenerative Diseases: Inflammatory Cytokines and Bioactive Kynurenines
Masaru Tanaka, József Toldi, László Vécsei
International Journal of Molecular Sciences.2020; 21(7): 2431. CrossRef
Modeling Parkinson’s Disease With the Alpha-Synuclein Protein
Mónica Gómez-Benito, Noelia Granado, Patricia García-Sanz, Anne Michel, Mireille Dumoulin, Rosario Moratalla
Frontiers in Pharmacology.2020;[Epub] CrossRef
Enhanced Susceptibility of PINK1 Knockout Rats to α-Synuclein Fibrils
Rose B. Creed, Matthew S. Goldberg
Neuroscience.2020; 437: 64. CrossRef
Pathogenic Mutations Differentially Regulate Cell-to-Cell Transmission of α-Synuclein
Yuan Guan, Xiaofang Zhao, Fengwei Liu, Shuxin Yan, Yalong Wang, Cuilian Du, Xiuyu Cui, Rena Li, Claire Xi Zhang
Frontiers in Cellular Neuroscience.2020;[Epub] CrossRef
Dopamine, Alpha-Synuclein, and Mitochondrial Dysfunctions in Parkinsonian Eyes
Alessia Indrieri, Rocco Pizzarelli, Brunella Franco, Elvira De Leonibus
Frontiers in Neuroscience.2020;[Epub] CrossRef
Classic and evolving animal models in Parkinson's disease
Tanvi Pingale, Girdhari Lal Gupta
Pharmacology Biochemistry and Behavior.2020; 199: 173060. CrossRef

Oro-Pharyngeal Dysphagia in Parkinson’s Disease and Related Movement Disorders: Miseon Kwon, Jae-Hong Lee; J Mov Disord. 2019;12(3):152-160. Published online September 30, 2019; DOI: https://doi.org/10.14802/jmd.19048

41,139 View
1,118 Download
38 Web of Science
37 Crossref

Abstract PDF Supplementary Material

Oro-pharyngeal dysphagia is a common symptom in patients with Parkinson’s disease (PD) and related disorders, even in their early stage of diseases. Dysphagia in these patients has been underdiagnosed, probably due to poor the self-awareness of the conditions and the underuse of validated tools and objective instruments for assessment. The early detection and intervention of dysphagia are closely related to improving the quality of life and decreasing the mortality rate in these patients. The purpose of this paper is to give an overview of the characteristics of dysphagia, including the epidemiology, pathophysiology, and clinical symptomatology, in patients with PD compared with other parkinsonian disorders and movement disorders. The management of dysphagia and future research directions related to these disorders are also discussed.

Citations

Citations to this article as recorded by

The missing piece of the puzzle – The key role of the dietitian in the management of Parkinson's disease
Richelle Flanagan, Carley Rusch, Fiona E. Lithander, Indu Subramanian
Parkinsonism & Related Disorders.2024; 121: 106021. CrossRef
Quantitative evaluation of swallowing function in Parkinson’s disease using tongue pressure measurement: a mini-review
Tatsuyuki Fukuoka, Kazuhiro Hori, Takahiro Ono
Frontiers in Neurology.2024;[Epub] CrossRef
Dysphagia Presentation, Airway Invasion, and Gender Differences in a Clinically Based Sample of People with Parkinson’s Disease
Matthew Dumican, Christopher Watts, Teresa Drulia, Yan Zhang
Dysphagia.2023; 38(1): 353. CrossRef
An intensive neurorehabilitation programme with sEMG biofeedback to improve swallowing in idiopathic Parkinson's disease (IPD): A feasibility study
Irene Battel, Margaret Walshe
International Journal of Language & Communication Disorders.2023; 58(3): 813. CrossRef
Tongue strength and clinical correlations in Parkinson's disease
Exequiel Plaza, Angela Ruviaro Busanello‐Stella
Journal of Oral Rehabilitation.2023; 50(4): 300. CrossRef
Pathophysiology of non-motor signs in Parkinson’s disease: some recent updating with brief presentation
Khaled Radad, Rudolf Moldzio, Christopher Krewenka, Barbara Kranner, Wolf-Dieter Rausch
Exploration of Neuroprotective Therapy.2023; : 24. CrossRef
Pink1-/- Rats Demonstrate Swallowing and Gastrointestinal Dysfunction in a Model of Prodromal Parkinson Disease
Maryann N. Krasko, John Szot, Karolina Lungova, Linda M. Rowe, Glen Leverson, Cynthia A. Kelm-Nelson, Michelle R. Ciucci
Dysphagia.2023; 38(5): 1382. CrossRef
Dysphagia in Parkinson Disease: Part I – Pathophysiology and Diagnostic Practices
Denis Michael Rudisch, Maryann N. Krasko, Ryan Burdick, Courtney K. Broadfoot, Nicole Rogus-Pulia, Michelle R. Ciucci
Current Physical Medicine and Rehabilitation Reports.2023; 11(2): 176. CrossRef
Dysphagia Requiring Medical Attention in Parkinson’s Disease: A Korean Population-Based Study
Seungwoo Cha, Won Kee Chang, Hee-Mun Cho, Kyungdo Han, Nam-Jong Paik, Sohyun Kwon, Won-Seok Kim
Journal of Korean Medical Science.2023;[Epub] CrossRef
A systematic review and meta-analysis of acupuncture in Parkinson's disease with dysphagia
Jing Wu, Yi Wang, Xueyan Wang, Yujia Xie, Weihong Li
Frontiers in Neurology.2023;[Epub] CrossRef
Chaudhuri’s Dashboard of Vitals in Parkinson’s syndrome: an unmet need underpinned by real life clinical tests
Mubasher A. Qamar, Silvia Rota, Lucia Batzu, Indu Subramanian, Cristian Falup-Pecurariu, Nataliya Titova, Vinod Metta, Iulia Murasan, Per Odin, Chandrasekhara Padmakumar, Prashanth L. Kukkle, Rupam Borgohain, Rukmini Mridula Kandadai, Vinay Goyal, Kallol
Frontiers in Neurology.2023;[Epub] CrossRef
Orofacial function and temporomandibular disorders in Parkinson’s Disease: a case-controlled study
Sara Baram, Carsten Eckhart Thomsen, Esben Boeskov Øzhayat, Merete Karlsborg, Merete Bakke
BMC Oral Health.2023;[Epub] CrossRef
Laryngeal symptoms related to motor phenotypes in Parkinson's disease: A systematic review
Zoe Thijs, Matthew Dumican
Laryngoscope Investigative Otolaryngology.2023; 8(4): 970. CrossRef
Transadaptation and Validation of the Telugu Version of the Dysphagia Handicap Index
Philemon Benison Dasari, Himanshu Verma, Harisha Madishetty, Jothirmai Pagidimarri, Janaki Balaji
Seminars in Speech and Language.2023; 44(04): 230. CrossRef
Progression of Self-Perceived Speech and Swallowing Impairment in Early Stage Parkinson's Disease: Longitudinal Analysis of the Unified Parkinson's Disease Rating Scale
Christopher R. Watts, Yan Zhang
Journal of Speech, Language, and Hearing Research.2022; 65(1): 146. CrossRef
Terminal Choking in Parkinson's Disease
Andrea Ling, Fiona Herbert, Bethany Wright, Edward Richfield
Journal of Pain and Symptom Management.2022; 63(6): e757. CrossRef
Effects of a tongue training program in Parkinson's disease: Analysis of electrical activity and strength of suprahyoid muscles
Exequiel Plaza, Angela Ruviaro Busanello-Stella
Journal of Electromyography and Kinesiology.2022; 63: 102642. CrossRef
Antidepressants Usage and Risk of Pneumonia Among Elderly Patients With the Parkinson's Disease: A Population-Based Case-Control Study
Wei-Yin Kuo, Kuang-Hua Huang, Yu-Hsiang Kuan, Yu-Chia Chang, Tung-Han Tsai, Chien-Ying Lee
Frontiers in Medicine.2022;[Epub] CrossRef
Neuropathological Aspects of SARS-CoV-2 Infection: Significance for Both Alzheimer’s and Parkinson’s Disease
Jaime Silva, Felipe Patricio, Aleidy Patricio-Martínez, Gerardo Santos-López, Lilia Cedillo, Yousef Tizabi, Ilhuicamina Daniel Limón
Frontiers in Neuroscience.2022;[Epub] CrossRef
Identifying rates and risk factors for medication errors during hospitalization in the Australian Parkinson’s disease population: A 3-year, multi-center study
Michael Bakker, Michaela E. Johnson, Lauren Corre, Deanna N. Mill, Xingzhuo Li, Richard J. Woodman, Jacinta L. Johnson, Ismaeel Yunusa
PLOS ONE.2022; 17(5): e0267969. CrossRef
Vegetable finger foods - Preferences among older adults with motoric eating difficulties
Sarah Forsberg, Viktoria Olsson, Wender L.P. Bredie, Karin Wendin
International Journal of Gastronomy and Food Science.2022; 28: 100528. CrossRef
Swallow Safety and Laryngeal Kinematics: A Comparison of Dysphagia Between Parkinson’s Disease and Cerebrovascular Accident
Matthew Dumican, Christopher Watts
Journal of Parkinson's Disease.2022; : 1. CrossRef
Parkinson Hastalığında Yutma Bozukluklarına Yaklaşım
Merve SAPMAZ ATALAR, Gençer GENÇ
Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi.2022; 9(2): 189. CrossRef
Swallow Safety and Laryngeal Kinematics: A Comparison of Dysphagia Between Parkinson’s Disease and Cerebrovascular Accident
Matthew Dumican, Christopher Watts
Journal of Parkinson's Disease.2022; 12(7): 2147. CrossRef
The prevalence and associated factors of dysphagia in Parkinson's disease: A systematic review and meta-analysis
Siyuan Gong, Yan Gao, Jihong Liu, Jia Li, Xueqin Tang, Qian Ran, Rongzhu Tang, Chunlian Liao
Frontiers in Neurology.2022;[Epub] CrossRef
Cardiac sympathetic denervation could be associated with dysphagia in Parkinson's disease
Jinyoung Youn, George Umemoto, Eungseok Oh, Jinse Park, Wooyoung Jang, Yoon-Sang Oh, Hee-Tae Kim, Jin Whan Cho, Shinsuke Fujioka, Yoshio Tsuboi
Frontiers in Neurology.2022;[Epub] CrossRef
Sensory preferences and requirements amongst Swedish older adults with motoric eating difficulties
Sarah Forsberg, Wender Bredie, Karin Wendin
Food & Nutrition Research.2022;[Epub] CrossRef
Effectiveness of pharmacologic treatment for dysphagia in Parkinson’s disease: a narrative review
Min Cheol Chang, Jin-Sung Park, Byung Joo Lee, Donghwi Park
Neurological Sciences.2021; 42(2): 513. CrossRef
The Effect of Deep Brain Stimulation on Swallowing Function in Parkinson’s Disease: A Narrative Review
Min Cheol Chang, Jin-Sung Park, Byung Joo Lee, Donghwi Park
Dysphagia.2021; 36(5): 786. CrossRef
Assessment of real life eating difficulties in Parkinson’s disease patients by measuring plate to mouth movement elongation with inertial sensors
Konstantinos Kyritsis, Petter Fagerberg, Ioannis Ioakimidis, K. Ray Chaudhuri, Heinz Reichmann, Lisa Klingelhoefer, Anastasios Delopoulos
Scientific Reports.2021;[Epub] CrossRef
Is Dysphagia in Older Patients with Parkinson’s Disease Associated With Sarcopenia?
Ebru Umay, Z.A. Yigman, E.A. Ozturk, I. Gundogdu, B.G. Koçer
The Journal of nutrition, health and aging.2021; 25(6): 742. CrossRef
Does Etiology Matter? Comparative Analysis of a Singing-Enhanced Swallowing Protocol for Patients with Neurological Impairment versus Head and Neck Cancer
Myung Sun Yeo, Ga Eul Yoo, Sung-Rae Cho, Soo Ji Kim
Brain Sciences.2021; 11(8): 997. CrossRef
Pneumonia Risk Associated with the Use of Individual Benzodiazepines and Benzodiazepine Related Drugs among the Elderly with Parkinson’s Disease
Kuang-Hua Huang, Chih-Jaan Tai, Yu-Hsiang Kuan, Yu-Chia Chang, Tung-Han Tsai, Chien-Ying Lee
International Journal of Environmental Research and Public Health.2021; 18(17): 9410. CrossRef
Videofluoroscopic study of swallowing disorders in patients with parkinsonism
Shivani Rajeev, Sureshkumar Radhakrishnan, Sivakumar Vidhyadharan, Unnikrishnan Menon, Krishnakumar Thankappan, Subramania Iyer
Amrita Journal of Medicine.2021; 17(3): 93. CrossRef
Predicting Airway Invasion Using Screening Tools and Laryngeal Kinematics in People with Parkinson’s Disease: A Pilot Study
Matthew Dumican, Christopher Watts
Journal of Parkinson's Disease.2020; 10(3): 1153. CrossRef
A comprehensive review of the diagnosis and treatment of Parkinson’s disease dysphagia and aspiration
Bhavana Patel, Joseph Legacy, Karen W. Hegland, Michael S. Okun, Nicole E. Herndon
Expert Review of Gastroenterology & Hepatology.2020; 14(6): 411. CrossRef
Pramipexole thermosensitive nasal gel for experimental parkinsonism in rats
Vinay Sridhar, Ankit Tiwari, Sarika Wairkar, Girdhari Lal Gupta, Ram Gaud
Journal of Drug Delivery Science and Technology.2020; 59: 101954. CrossRef

Viewpoint

Recent Advances in the Development of Experimental Therapeutics for Levodopa-Induced Dyskinesia: Michael L. Martini, Sean N. Neifert, J Mocco, Fedor Panov, Winona Tse, Ruth H. Walker, Jian Jin, Fiona Gupta; J Mov Disord. 2019;12(3):161-165. Published online September 30, 2019; DOI: https://doi.org/10.14802/jmd.19029

6,313 View
198 Download
2 Web of Science
1 Crossref

PDF

Citations

Citations to this article as recorded by

Antioxidant Effect of Alpha-Lipoic Acid in 6-Hydroxydopamine Unilateral Intrastriatal Injected Rats
Pavlina Andreeva-Gateva, Lubomir Traikov, Zafer Sabit, Dimitar Bakalov, Radka Tafradjiiska-Hadjiolova
Antioxidants.2020; 9(2): 122. CrossRef

Original Articles

Increased Signal in the Superior Cerebellar Peduncle of Patients with Progressive Supranuclear Palsy: Hiroshi Kataoka, Yukako Nishimori, Takao Kiriyama, Hitoki Nanaura, Tesseki Izumi, Nobuyuki Eura, Naoki Iwasa, Kazuma Sugie; J Mov Disord. 2019;12(3):166-171. Published online August 9, 2019; DOI: https://doi.org/10.14802/jmd.19002

8,477 View
220 Download
2 Web of Science
2 Crossref

Abstract PDF

Objective
The provisional diagnosis of progressive supranuclear palsy (PSP) depends on a combination of typical clinical features and specific MRI findings, such as atrophy of the tegmentum in the midbrain. Atrophy of the superior cerebellar peduncle (SCP) distinguishes PSP from other types of parkinsonism. Histological factors affect the conventional fluid-attenuated inversion recovery (FLAIR) signals, such as the extent of neuronal loss and gliosis.
Methods
We investigated patients with PSP to verify the percentage of patients with various PSP phenotypes presenting a high signal intensity in the SCP. Three interviewers, who were not informed about the clinical data, visually inspected the presence or absence of a high signal intensity in the SCP on the FLAIR images. We measured the pixel value in the SCP of each patient. Clinical characteristics were evaluated using the Mann-Whitney test, followed by the χ² test.
Results
Ten of the 51 patients with PSP showed a high signal intensity in the SCP on FLAIR MRI. Higher pixel values were observed within the SCP of patients with a high signal intensity in the SCP than in patients without a high signal intensity (p < 0.001). The sensitivity and specificity of the high signal intensity in the SCP of patients with PSP was 19.6% and 100%, respectively. This finding was more frequently observed in patients with PSP with Richardson’s syndrome (PSP-RS) (25.7%) than other phenotypes (6.2%).
Conclusion
The high signal intensity in the SCP on FLAIR MRI might be an effective diagnostic tool for PSP-RS.

Citations

Citations to this article as recorded by

Diffusion tractography of superior cerebellar peduncle and dentatorubrothalamic tracts in two autopsy confirmed progressive supranuclear palsy variants: Richardson syndrome and the speech-language variant
Rodolfo G. Gatto, Peter R. Martin, Farwa Ali, Heather M. Clark, Joseph R. Duffy, Rene L. Utianski, Hugo Botha, Mary M. Machulda, Dennis W. Dickson, Keith A. Josephs, Jennifer L. Whitwell
NeuroImage: Clinical.2022; 35: 103030. CrossRef
The Role of Magnetic Resonance Imaging for the Diagnosis of Atypical Parkinsonism
Lydia Chougar, Nadya Pyatigorskaya, Bertrand Degos, David Grabli, Stéphane Lehéricy
Frontiers in Neurology.2020;[Epub] CrossRef

The Impact of Impulsivity on Quality of Life in Early Drug-Naïve Parkinson’s Disease Patients: Dong-Woo Ryu, Joong-Seok Kim, Sang-Won Yoo, Yoon-Sang Oh, Kwang-Soo Lee; J Mov Disord. 2019;12(3):172-176. Published online August 9, 2019; DOI: https://doi.org/10.14802/jmd.19004; Correction in: J Mov Disord 2021;14(2):176

5,308 View
107 Download
7 Web of Science
6 Crossref

Abstract PDF

Objective
Impulse control disorders (ICDs) in Parkinson’s disease (PD) are mostly related to dopamine replacement therapy (DRT); however, drug-naïve PD patients have also frequently experienced impulsivity. This phenomenon makes clinicians hesitate treating patients with DRT. In this study, we assessed the effect of impulsivity on quality of life (QOL) in drug-naïve PD patients.
Methods
Two hundred three newly diagnosed, nonmedicated PD patients were enrolled, and they received structured clinical interviews, physical examinations and validated questionnaires to evaluate motor and nonmotor symptoms and QOL. Impulsivity was evaluated using the Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s Disease-Rating Scale (QUIP-RS).
Results
Thirty-eight patients (18.7%) had impulsivity with QUIP-RS scores ≥ 1 and 4 patients (2.0%) were diagnosed with combined ICDs. Motor and nonmotor symptoms were significantly correlated with the Parkinson’s Disease Questionnaire-39 summary index. Female sex and QUIP-RS scores were also correlated with QOL in drug-naïve PD patients.
Conclusion
The results of the present study showed that impulsivity negatively influences QOL in early drug-naïve PD patients. In addition, more severe motor and nonmotor symptoms were also associated with lower QOL. Such findings complicate treatment but provide valuable information for managing early PD.

Citations

Citations to this article as recorded by

Frequency of Impulsive-Compulsive Behavior and Associated Psychological Factors in Parkinson’s Disease: Lack of Control or Too Much of It?
Alexandros Kapsomenakis, Dimitrios Kasselimis, Emily Vaniotis, Anastasia Bougea, Christos Koros, Athina Maria Simitsi, Leonidas Stefanis, Constantin Potagas
Medicina.2023; 59(11): 1942. CrossRef
Locus Coeruleus Integrity Is Linked to Response Inhibition Deficits in Parkinson's Disease and Progressive Supranuclear Palsy
Rong Ye, Frank H. Hezemans, Claire O'Callaghan, Kamen A. Tsvetanov, Catarina Rua, P. Simon Jones, Negin Holland, Maura Malpetti, Alexander G. Murley, Roger A. Barker, Caroline H. Williams-Gray, Trevor W. Robbins, Luca Passamonti, James B. Rowe
The Journal of Neuroscience.2023; 43(42): 7028. CrossRef
Neuropsychiatric Symptoms in Parkinson's Disease After Subthalamic Nucleus Deep Brain Stimulation
Weibing Liu, Tatsuya Yamamoto, Yoshitaka Yamanaka, Masato Asahina, Tomoyuki Uchiyama, Shigeki Hirano, Keisuke Shimizu, Yoshinori Higuchi, Satoshi Kuwabara
Frontiers in Neurology.2021;[Epub] CrossRef
Dopamine genetic risk score predicts impulse control behaviors in Parkinson’s disease
Alison Hall, Samuel R. Weaver, Lindsey J. Compton, Winston D. Byblow, Ned Jenkinson, Hayley J. MacDonald
Clinical Parkinsonism & Related Disorders.2021; 5: 100113. CrossRef
A Review of the Concept of Impulsivity
Mohammed Munther Al-Hammouri, Jehad A. Rababah, Celeste Shawler
Advances in Nursing Science.2021; 44(4): 357. CrossRef
Assessment of therapeutic strategies for management of impulse control disorder in Parkinson’s disease
Mayela Rodríguez-Violante, Yazmín Ríos-Solís, Oscar Esquivel-Zapata, Fanny Herrera, Susana López-Alamillo, Cynthia Sarabia-Tapia, Amin Cervantes-Arriaga
Arquivos de Neuro-Psiquiatria.2021; 79(11): 989. CrossRef

Clinical Milestones Preceding the Diagnosis of Multiple System Atrophy and Progressive Supranuclear Palsy: A Retrospective Cohort Study: Louise Wiblin, Rory Durcan, Brook Galna, Mark Lee, David Burn; J Mov Disord. 2019;12(3):177-183. Published online August 9, 2019; DOI: https://doi.org/10.14802/jmd.19015

7,498 View
212 Download
3 Web of Science
5 Crossref

Abstract PDF

Objective
Multiple System Atrophy (MSA) and progressive supranuclear palsy (PSP) are rapidly progressive forms of degenerative Parkinsonism. The difficulties of diagnosing MSA and PSP in their early stages may lead to delayed referral to appropriate specialists and distress to patients, as well as delaying symptomatic treatment and participation in clinical trials. This work aimed to describe the symptoms that patients with MSA and PSP developed and plot their emergence relative to final diagnosis using a median onset in months.
Methods
Forty-seven patients from the United Kingdom with MSA or PSP diagnosed by a movement disorder specialist were interviewed with carers or relatives to establish milestone onset. This was corroborated using clinical notes and letters.
Results
In the MSA cohort (n = 23), autonomic symptoms (median 5.5 months before diagnosis) and falls (median 1 month before diagnosis) were the two clinical milestones which occurred before diagnosis. In the PSP cohort (n = 24), falling was the only milestone which occurred before diagnosis (median of 18.5 months).
Conclusion
This Study Shows That Psp Patients Experience Falling More Than A Year And A Half An Average Before Receiving A Diagnosis And Although Msa Patients Also Tended To Fall, This Was Much Closer To The Time Of Diagnosis. Further Work With Larger Cohorts May Illustrate Whether These Preliminary Findings Can Be Generalised To Guide Diagnosis And Management.

Citations

Citations to this article as recorded by

Clinical milestones as triggers for palliative care intervention in progressive Supranuclear palsy and multiple system atrophy
Robin Bessemer, Alla Iansavichene, Mary E. Jenkins, Elizabeth Finger, Teneille E. Gofton
Journal of the Neurological Sciences.2023; 448: 120614. CrossRef
Toward More Accessible Fully Automated 3D Volumetric MRI Decision Trees for the Differential Diagnosis of Multiple System Atrophy, Related Disorders, and Age-Matched Healthy Subjects
Jisoo Kim, Geoffrey S. Young, Andrew S. Willett, Ariana T. Pitaro, Grace F. Crotty, Merlyne Mesidor, Kristie A. Jones, Camden Bay, Min Zhang, Mel B. Feany, Xiaoyin Xu, Lei Qin, Vikram Khurana
The Cerebellum.2022; 22(6): 1098. CrossRef
Disease course and treatment patterns in progressive supranuclear palsy: A real-world study
John C. Morgan, Xiaolan Ye, Jennifer A. Mellor, Keisha J. Golden, Jorge Zamudio, Louis A. Chiodo, Yanjun Bao, Tao Xie
Journal of the Neurological Sciences.2021; 421: 117293. CrossRef
Patient and care partner views on exercise and structured physical activity for people with Progressive Supranuclear Palsy
Susan C. Slade, Christopher Bruce, Jennifer L. McGinley, Bastiaan R. Bloem, Meg E. Morris, John Duda
PLOS ONE.2020; 15(6): e0234265. CrossRef
Effect of cold oral stimulation on orthostatic hypotension in multiple system atrophy: a case study
Hironobu Uzawa, Shinta Takeuchi, Yusuke Nishida
Journal of Physical Therapy Science.2020; 32(7): 473. CrossRef

Letters to the editor

Fragile X-Associated Tremor/Ataxia Syndrome: An Illustrative Case: Chaewon Lee, Kye Won Park, Nari Choi, Ho-Sung Ryu, Sun Ju Chung; J Mov Disord. 2019;12(3):184-186. Published online July 17, 2019; DOI: https://doi.org/10.14802/jmd.18060

5,515 View
119 Download
2 Web of Science
2 Crossref

PDF

Citations

Citations to this article as recorded by

A Case of Fragile-X-Associated Tremor/Ataxia Syndrome Without Tremor
Woong-Woo Lee, Byung-Kun Kim, Jung Ju Lee, Kyusik Kang
Journal of Clinical Neurology.2023; 19(5): 498. CrossRef
Brain 18F-FDG and 18F-Flumetamol PET Imaging of Fragile X-Associated Tremor Ataxia Syndrome
Ruggero Bacchin, Matteo Salgarello, Michela Trentin, Giampietro Zanette, Stefano Tamburin
Clinical Nuclear Medicine.2021; 46(7): e344. CrossRef

Hyperglycemia-Associated Hemichorea-Hemiballismus with Predominant Ipsilateral Putaminal Abnormality on Neuroimaging: Si Lei Fong, Ai Huey Tan, Kar Foo Lau, Norlisah Ramli, Shen-Yang Lim; J Mov Disord. 2019;12(3):187-189. Published online August 9, 2019; DOI: https://doi.org/10.14802/jmd.19014

6,717 View
167 Download
7 Web of Science
5 Crossref

PDF Supplementary Material

Citations

Citations to this article as recorded by

Relationship Between Diabetic Chorea and Timing of MRI Findings: A Systematic Review with Case Reports
Yumi Otaka, Yukinori Harada, Norio Sugawara, Taro Shimizu, Norio Yasui-Furukori
International Journal of General Medicine.2023; Volume 16: 4465. CrossRef
The Possible Precipitating Role of SARS-CoV-2 in a Case of Late-Onset Hemichorea Due to a Hyperosmolar Hyperglycemic State: Case Report and Brief Literature Review
Roberto Sperotto, Laura Ceccarelli, Yan Tereshko, Giovanni Merlino, Gian Luigi Gigli, Mariarosaria Valente
Medicina.2023; 59(11): 1949. CrossRef
Consideration for Hemiballismus in the Differential Diagnosis: A Rare Case of Hyperosmolar Hyperglycemic State
Iman Isayli, Nicolas Ulloa, John Childress
Cureus.2022;[Epub] CrossRef
A Case of Diabetic Hemichorea Hemiballismus Exacerbated by Hypoglycemia
Jessica Rupp, Avrum Gillespie
AACE Clinical Case Reports.2021;[Epub] CrossRef
Hemicorea inducida por hiperglucemia no cetósica: discordancia clínicorradiológica
Juan Pablo García Marmolejo, Manuel David Mayoral Valencia, Paola Andrea Tejada Serna
Universitas Médica.2021;[Epub] CrossRef

Successful Pallidal Deep Brain Stimulation in a Patient with Childhood-Onset Generalized Dystonia with ANO3 Mutation: Dallah Yoo, Han-Joon Kim, Jong-Hee Chae, Sun Ha Paek, Beomseok Jeon; J Mov Disord. 2019;12(3):190-191. Published online July 17, 2019; DOI: https://doi.org/10.14802/jmd.19016

5,301 View
120 Download
8 Web of Science
9 Crossref

PDF Supplementary Material

Citations

Citations to this article as recorded by

The Clinical Spectrum of ANO3—Report of a New Family and Literature Review
Marco Percetti, Michela Zini, Paola Soliveri, Filippo Cogiamanian, Mariarosa Ferrara, Eva Orunesu, Alessandra Ranghetti, Carlo Ferrarese, Gianni Pezzoli, Barbara Garavaglia, Ioannis Ugo Isaias, Giorgio Sacilotto
Movement Disorders Clinical Practice.2024; 11(3): 289. CrossRef
The role of genetics in the treatment of dystonia with deep brain stimulation: Systematic review and Meta-analysis
Harini Sarva, Federico Rodriguez-Porcel, Francisco Rivera, Claudio Daniel Gonzalez, Samantha Barkan, Susmit Tripathi, Emilia Gatto, Pedro Garcia Ruiz
Journal of the Neurological Sciences.2024; 459: 122970. CrossRef
A novel ANO3 variant in two siblings with different phenotypes
Marcello Esposito, Assunta Trinchillo, Francesca Piceci-Sparascio, Maria Cecilia D'Asdia, Federica Consoli, Alessandro De Luca
Parkinsonism & Related Disorders.2023; 111: 105413. CrossRef
DBS-Evoked Pallidal Activity Correlates with Clinical Improvement in a Patient with ANO3-Related Dystonia
Aditya Boddu, Adam Bashir, Mohammad Awad, Barton Guthrie, Harrison Walker
SSRN Electronic Journal.2023;[Epub] CrossRef
Deep Brain Stimulation in Dystonia: Disentangling Heterogeneity
Alberto Albanese
Movement Disorders Clinical Practice.2021; 8(1): 6. CrossRef
Pallidal Deep Brain Stimulation for Monogenic Dystonia: The Effect of Gene on Outcome
Stephen Tisch, Kishore Raj Kumar
Frontiers in Neurology.2021;[Epub] CrossRef
The expanding clinical and genetic spectrum of ANO3 dystonia
Li-Ting Jiang, Li-Xi Li, Ying Liu, Xiao-Long Zhang, You-Gui Pan, Lin Wang, Xin-Hua Wan, Ling-Jing Jin
Neuroscience Letters.2021; 746: 135590. CrossRef
Huntington disease-like phenotype in a patient with ANO3 mutation
Shahedah Koya Kutty, Eoin Mulroy, Francesca Magrinelli, Giulia Di Lazzaro, Anna Latorre, Kailash P. Bhatia
Parkinsonism & Related Disorders.2021; 90: 120. CrossRef
Arching deep brain stimulation in dystonia types
Han-Joon Kim, Beomseok Jeon
Journal of Neural Transmission.2021; 128(4): 539. CrossRef

Benefits of Levodopa-Carbidopa Intestinal Gel Infusion in Patients with Parkinson’s Disease Experiencing Gait Dysfunction Following Subthalamic Deep Brain Stimulation: Thomas Edmund Kimber, YiZhong Zhuang, Philip Douglas Thompson; J Mov Disord. 2019;12(3):192-194. Published online September 30, 2019; DOI: https://doi.org/10.14802/jmd.19022

4,371 View
68 Download
2 Web of Science
2 Crossref

PDF Supplementary Material

Citations

Citations to this article as recorded by

Nationwide Retrospective Analysis of Combinations of Advanced Therapies in Patients With Parkinson Disease
Dominik Pürner, Mohammad Hormozi, Daniel Weiß, Michael T. Barbe, Hannah Jergas, Tino Prell, Eileen Gülke, Monika Pötter-Nerger, Björn Falkenburger, Lisa Klingelhöfer, Pia K. Gutsmiedl, Bernhard Haslinger, Angela M. Jochim, Andreas Wolff, Nils Schröter, Mi
Neurology.2023;[Epub] CrossRef
Combined and Sequential Treatment with Deep Brain Stimulation and Continuous Intrajejunal Levodopa Infusion for Parkinson’s Disease
Daniël van Poppelen, Annelie N.M. Tromp, Rob M.A. de Bie, Joke M. Dijk
Journal of Personalized Medicine.2021; 11(6): 547. CrossRef

Hemichorea-Hemiballism after External Ventricular Drainage: Mirza Masoom Abbas, Ravi Gopal Varma, Nirmala Sankar, Raghavendra Pai; J Mov Disord. 2019;12(3):195-197. Published online September 30, 2019; DOI: https://doi.org/10.14802/jmd.19033

4,317 View
61 Download
1 Web of Science
1 Crossref

PDF Supplementary Material

Citations

Citations to this article as recorded by

Efficacy and safety profile of neuroendoscopic hematoma evacuation combined with intraventricular lavage in severe intraventricular hemorrhage patients
Hai‐Tao Ding, Yao Han, De‐Ke Sun, Quan‐Min Nie
Brain and Behavior.2020;[Epub] CrossRef

First
Prev
Page of 1
Next
Last

Previous issues